Clinical Trials Logo
  1. Home
  2. Pain
  3. NCT02595476
  4. Details
NCT02595476 Clinical Trial

Influence of Depth of Anesthesia on Pupillary Reactivity to a Standardized Stimulus

Pain Clinical Trial

Official title:
The Influence of Depth of Anesthesia on Pupillary Reactivity to a Standardized Stimulus Under Steady-state Remifentanil Analgesia

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02595476
Other study ID # Anesthésie Trousseau 002
Secondary ID
Status Completed
Phase N/A
First received November 2, 2015
Last updated March 31, 2017
Start date January 2015
Est. completion date March 2016

Study information
Verified date March 2017
Source Hôpital Armand Trousseau
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

A standardized tetanic stimulation is applied to patients under propofol-remifentanil TCI, in a cross-over fashion, at two different levels of anesthesia monitored by the BIS: BIS 25 and BIS 55. Remifentanil target remains constant during the whole study period (1 ng/ml). Pupillary reflex dilation is recorded after each stimulation.

Recruitment information / eligibility
Status Completed
Enrollment 12
Est. completion date March 2016
Est. primary completion date January 2016
Accepts healthy volunteers No
Gender All
Age group 10 Years to 20 Years
Eligibility Inclusion Criteria:

- ASA 1-2

- scheduled for an idiopathic scoliosis surgical correction

Exclusion Criteria:

- Ophtalmologic pathology

- Neurologic or muscular pathology

- Metabolic pathology

- Chronic pain

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Remifentanil

• propofol

Device:
• TCI

Procedure:
• Tetanic stimulation

Device:
• Algiscan
Pupillometry

Locations
Country Name City State
France Departement d'anesthesie Hopital Armand Trousseau Paris

Sponsors (1)
Lead Sponsor Collaborator
Hôpital Armand Trousseau

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary Post-stimulation Pupillary reflex dilation percentage of dilation compared to pre-stimulation pupillary diameter 30 seconds
See also
  Status Clinical Trial Phase
Active, not recruiting NCT05559255 - Changes in Pain, Spasticity, and Quality of Life After Use of Counterstrain Treatment in Individuals With SCI N/A
Completed NCT04748367 - Leveraging on Immersive Virtual Reality to Reduce Pain and Anxiety in Children During Immunization in Primary Care N/A
Terminated NCT04356352 - Lidocaine, Esmolol, or Placebo to Relieve IV Propofol Pain Phase 2/Phase 3
Completed NCT05057988 - Virtual Empowered Relief for Chronic Pain N/A
Completed NCT04466111 - Observational, Post Market Study in Treating Chronic Upper Extremity Limb Pain
Recruiting NCT06206252 - Can Medical Cannabis Affect Opioid Use?
Completed NCT05868122 - A Study to Evaluate a Fixed Combination of Acetaminophen/Naproxen Sodium in Acute Postoperative Pain Following Bunionectomy Phase 3
Active, not recruiting NCT05006976 - A Naturalistic Trial of Nudging Clinicians in the Norwegian Sickness Absence Clinic. The NSAC Nudge Study N/A
Completed NCT03273114 - Cognitive Functional Therapy (CFT) Compared With Core Training Exercise and Manual Therapy (CORE-MT) in Patients With Chronic Low Back Pain N/A
Enrolling by invitation NCT06087432 - Is PNF Application Effective on Temporomandibular Dysfunction N/A
Completed NCT05508594 - Efficacy and Pharmacokinetic-Pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001 Phase 2/Phase 3
Recruiting NCT03646955 - Partial Breast Versus no Irradiation for Women With Early Breast Cancer N/A
Active, not recruiting NCT03472300 - Prevalence of Self-disclosed Knee Trouble and Use of Treatments Among Elderly Individuals
Completed NCT03678168 - A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries N/A
Completed NCT03931772 - Online Automated Self-Hypnosis Program N/A
Completed NCT03286543 - Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta System N/A
Completed NCT02913027 - Can We Improve the Comfort of Pelvic Exams? N/A
Terminated NCT02181387 - Acetaminophen Use in Labor - Does Use of Acetaminophen Reduce Neuraxial Analgesic Drug Requirement During Labor? Phase 4
Recruiting NCT06032559 - Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment Phase 3
Active, not recruiting NCT03613155 - Assessment of Anxiety in Patients Treated by SMUR Toulouse and Receiving MEOPA as Part of Their Care