Pain Clinical Trial
Official title:
Peritonsillar Infiltration With Levobupivacaine for Relief of Posttonsillectomy Pain: Does Concentration Have Any Effect?
The investigators aimed to evaluate the effects of different concentrations of preincisional peritonsillar levobupivacaine (0.25% ve 0.5%) on postoperative pain and bleeding
72 ASA I-II patients between 3 and 12 years of age who scheduled to undergo tonsillectomy
were enrolled in this randomized, prospective and placebo-controlled study. The indications
for tonsillectomy were recurrent infections and tonsillar hypertrophy leading to obstructive
symptoms.
The patients included to the study were randomly assigned to one of the 3 groups to receive
different concentrations of levobupivacaine or saline.
The mean arterial pressure (MAP) and heart rates (HR) of all patients were recorded during
the whole anesthesia and surgical procedures. The duration of anesthesia and surgery were
also recorded. Additional remifentanil 1 µgr kg-1 IV was administered to the patients if HR
was increased by 25 % of the basal value.
During postoperative period, symptoms such as pain, fever and dysphagia, adverse affects
such as nausea and vomiting and hemorrhage were evaluated. Pain was evaluated by FLACC
(Faces, leg, activity, cry, consolability), FPRS (Faces pain rating scale) ve Wong-Baker
facies scales at postoperative 0, 30 and 60 minutes and 2, 6, 12 and 24 hours. Total
analgesic consumption during the postoperative period were recorded. If the patients had no
complication, they were discharged at the postoperative 24th hour.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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