Pain Clinical Trial
Official title:
Cervical Priming With Misoprostol Before Diagnostic Office Hysteroscopy in Patients With no Risk Factors for Experiencing Unacceptable Pain. A Randomized Double Blinded Placebo-controlled Study
The aim of this study is to assess whether vaginal misoprostol reduces pain during office hysteroscopy in parous patients with no risk factors for experiencing severe or unacceptable pain.
Cervical ripening with misoprostol to minimize the pain experienced during office
hysteroscopy has been proposed by several authors.
The use of misoprostol is usually associated with undesired side effects and therefore any
beneficial effect of misoprostol on reducing pain should be weighed against its undesired
side effects (nausea, vomiting, diarrhea, fever, shivering, pain) and coasts. Till now , no
studies have yet determined whether misoprostol should be used routinely or for the subgroup
of patients at higher risk for cervical stenosis.
The aim of this study is to assess whether vaginal misoprostol reduces pain during office
hysteroscopy in parous patients with no risk factors for experiencing severe or unacceptable
pain.
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
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