Pain Clinical Trial
Official title:
A Pilot Study of The Tandem Treatment of Painful Osseous Metastases With Cryoablation Followed by Radiation Therapy
This pilot clinical trial studies cryosurgery and radiation therapy in treating patients with painful bone metastases. Cryosurgery kills tumor cells by freezing them. Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells and shrink tumors. Giving cryosurgery together with radiation therapy may kill more tumor cells
PRIMARY OBJECTIVES:
I. To assess the potential for efficacy and safety of combining percutaneous computed
tomography (CT)-guided cryoablation and radiotherapy for the palliation of osseous
metastases.
OUTLINE:
Patients undergo cryosurgery. Beginning 2 weeks later, patients undergo 1, 10, or 15
fractions of radiation therapy 5 days per week for 1-3 weeks. Treatment continues in the
absence of disease progression or unacceptable toxicity.
After completion of study treatment, patients are followed up at 24 hours and weeks 1-2, 4,
12, 18, and 24.
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