Clinical Trials Logo
  1. Home
  2. Pain
  3. NCT01264965
  4. Details
NCT01264965 Clinical Trial

Non-cancer Pain and Cognitive Impairment: A Disabling Relationship

Pain Clinical Trial

Official title:
Opioids Versus Extra Strength Acetaminophen for the Management of Moderate Persistent Non-cancer Pain

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT01264965
Other study ID # 10-238-B
Secondary ID
Status Terminated
Phase Phase 4
First received
Last updated
Start date January 2011
Est. completion date February 2014

Study information
Verified date November 2020
Source University of Chicago
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

To compare the efficacy of long-acting oxycodone to extended-release acetaminophen in older persons with no and mild to moderate cognitive impairment and persistent moderate or higher intensity non-cancer lower extremity arthritis pain; and Describe the association of change in non-cancer pain self-report with an older adults functional status (BPI and WOMAC and brief physical performance measure) and to determine if cognitive status modifies this relationship.

Recruitment information / eligibility
Status Terminated
Enrollment 25
Est. completion date February 2014
Est. primary completion date February 2014
Accepts healthy volunteers No
Gender All
Age group 65 Years and older
Eligibility Inclusion Criteria: 1. age over 65 2. Pain at least 3 months duration 3. Pain greater in lower extremity than other anatomical site with ambulation 4. Pain self-report of moderate intensity of higher on an average day 5. Community-dwelling 6. Ambulatory 7. Physician states participants have decision-making capacity to enroll into the trial 8. Participants with cognitive impairment have a reliable caregiver 9. Inadequate pain relief from NSAIDS and/or acetaminophen in the past Exclusion Criteria: 1. Current cancer requiring chemotherapy 2. History of addiction to opioids or other controlled substance 3. Consumes more than 2 alcoholic drinks a day 4. Severe balance disturbance 5. Intra-articular steroid injection in the past 6 weeks

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• long acting oxycodone
10mg twice daily
• extra strength acetaminophen
1,000 mg twice daily

Locations
Country Name City State
United States University of Chicago Medical Center Outpatient Senior Health Center South Shore Chicago Illinois

Sponsors (1)
Lead Sponsor Collaborator
University of Chicago

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Pain Self-report on the Brief Pain Inventory and WOMAC 14 days
Secondary Discontinuation of Study Drug, Short Physical Performance Battery 14 days
See also
  Status Clinical Trial Phase
Active, not recruiting NCT05559255 - Changes in Pain, Spasticity, and Quality of Life After Use of Counterstrain Treatment in Individuals With SCI N/A
Terminated NCT04356352 - Lidocaine, Esmolol, or Placebo to Relieve IV Propofol Pain Phase 2/Phase 3
Completed NCT04748367 - Leveraging on Immersive Virtual Reality to Reduce Pain and Anxiety in Children During Immunization in Primary Care N/A
Completed NCT05057988 - Virtual Empowered Relief for Chronic Pain N/A
Completed NCT04466111 - Observational, Post Market Study in Treating Chronic Upper Extremity Limb Pain
Recruiting NCT06206252 - Can Medical Cannabis Affect Opioid Use?
Completed NCT05868122 - A Study to Evaluate a Fixed Combination of Acetaminophen/Naproxen Sodium in Acute Postoperative Pain Following Bunionectomy Phase 3
Active, not recruiting NCT05006976 - A Naturalistic Trial of Nudging Clinicians in the Norwegian Sickness Absence Clinic. The NSAC Nudge Study N/A
Completed NCT03273114 - Cognitive Functional Therapy (CFT) Compared With Core Training Exercise and Manual Therapy (CORE-MT) in Patients With Chronic Low Back Pain N/A
Enrolling by invitation NCT06087432 - Is PNF Application Effective on Temporomandibular Dysfunction N/A
Completed NCT05508594 - Efficacy and Pharmacokinetic-Pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001 Phase 2/Phase 3
Recruiting NCT03646955 - Partial Breast Versus no Irradiation for Women With Early Breast Cancer N/A
Active, not recruiting NCT03472300 - Prevalence of Self-disclosed Knee Trouble and Use of Treatments Among Elderly Individuals
Completed NCT03678168 - A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries N/A
Completed NCT03286543 - Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta System N/A
Completed NCT03931772 - Online Automated Self-Hypnosis Program N/A
Completed NCT02913027 - Can We Improve the Comfort of Pelvic Exams? N/A
Terminated NCT02181387 - Acetaminophen Use in Labor - Does Use of Acetaminophen Reduce Neuraxial Analgesic Drug Requirement During Labor? Phase 4
Recruiting NCT06032559 - Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment Phase 3
Active, not recruiting NCT03613155 - Assessment of Anxiety in Patients Treated by SMUR Toulouse and Receiving MEOPA as Part of Their Care