Attenuation of Pain in Men and Women

Pain Clinical Trial

Official title:

Attenuation of Pain in Men and Women: Mechanisms of Exercise-Induced Analgesia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01220414
• Other study ID #: H-2010-0087
• Status: Completed
• Phase: N/A
• First received: September 28, 2010
• Last updated: January 22, 2018
• Start date: September 2010
• Est. completion date: January 2013

Study information

• Verified date: January 2018
• Source: University of Wisconsin, Madison
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to examine opioid and endocannabinoid mechanisms of exercise-induced analgesia in men and women.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: January 2013
• Est. primary completion date: January 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria: Healthy men and women

Exclusion Criteria:

• current cardiac or other chronic diseases (e.g., cancer, diabetes, hypertension, kidney disease); routine use of prescriptive medications; history of vasovagal response to phlebotomy; an allergy to naltrexone; pregnancy; current smokers; current use of recreational drugs; history of substance abuse

Related Conditions & MeSH terms

• Pain

Intervention

Drug:
• Naltrexone, then placebo
50 mg of naltrexone
• Placebo, then Naltrexone
sugar pill

Locations

Country	Name	City	State
United States	University of Wisconsin-Madison	Madison	Wisconsin

Sponsors (1)

Lead Sponsor	Collaborator
University of Wisconsin, Madison

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Time for Subject to Reach Pain Threshold		Baseline