Analgesic Efficacy of Surgeon-administered Transversus Abdominis Plane Blocks for Caesarean Section.

Pain, Postoperative Clinical Trial

Official title:

Analgesic Efficacy of Surgeon-administered Transversus Abdominis Plane Blocks for Caesarean Section.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06324942
• Other study ID #: REB24-0349
• Status: Not yet recruiting
• Phase: N/A
• Start date: June 2024
• Est. completion date: December 2026

Study information

• Verified date: March 2024
• Source: University of Calgary
• Contact: Stephen Wood, MD
• Phone: 4039441438
• Email: slwood[@]ucalgary.ca
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this research study is to evaluate whether or not adding a Transversus Abdominis Plane Block (TAP block) improves pain control for patients having a cesarean section. A TAP block is a type of nerve block where at the end of the surgery an injection of a long acting local anesthetic is made into the abdominal wall. In studies in patient's having other abdominal surgeries this has reduced the amount of narcotics patients need for pain control. This may also led to patients being more active after surgery and maybe spending less time in hospital.

Description:

Randomized clinical trial of Transversus Abdominis Plane Block (TAP block) at Cesarean Section.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 80
• Est. completion date: December 2026
• Est. primary completion date: June 2026
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• ASA status II to III

• All patients undergoing elective CS under regional anesthesia at any gestational age.

Exclusion Criteria:

• - Known drug allergy to local anesthetics

• Planned general anesthetic

• NSAID use contraindicated post partum

• Chronic pain disorder or chronic narcotic use/dependence

• Planned vertical abdominal incision

• Planned Cesarean Hysterectomy.

• Placenta Previa or suspected Placenta Accreta

Related Conditions & MeSH terms

• Cesarean Section Complications
• Pain, Postoperative

Intervention

Other:
• Surgeon-administered Transversus Abdominis Plane Block 0.25% bupivicaine 0.25 mL/kg
Surgeon-administered Transversus Abdominis Plane Block

Locations

Country	Name	City	State
Canada	University of Calgary	Calgary	Alberta

Sponsors (1)

Lead Sponsor	Collaborator
University of Calgary

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Post operative Pain	VAS scale 0-no pain to 10-worst pain	12 hours post op
Secondary	Time to first request for rescue analgesia in hours	Time from completion of surgery to first request for rescue analgesia in hours	48 hours post op
Secondary	Post operative Opioid use	Total opioid consumption in the first 24h and 48h mark, postoperatively	up to 48 hours post op.
Secondary	Time from surgery to discharge from hospital	Time from completion of surgery to discharge	Up to discharge from hospital, usually 1-3 days