Effect of Different Local Anesthetic Volumes of Serratus Anterior Plan Block After Video-Assisted Thoracoscopic Surgery

Pain, Postoperative Clinical Trial

Official title:

The Effect of Different Local Anesthetic Volumes of Serratus Anterior Plan Block Performed With Ultrasound on Acute Pain After Video-Assisted Thoracoscopic Surgery

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05255536
• Other study ID #: E.Kurul-E1-22-2371
• Status: Recruiting
• Phase: N/A
• Start date: February 15, 2022
• Est. completion date: May 15, 2024

Study information

• Verified date: February 2024
• Source: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
• Contact: Musa Zengin, MD
• Phone: 903125677233
• Email: musazengin[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS. Analgesic methods such as thoracic paravertebral block (TPVB), intercostal block, serratus anterior plane block (SAPB), and erector spinae plane block (ESPB) are widely used for VATS. Among these methods, ultrasound (US) guided TPVB is the most preferred method. In recent years, the frequency of application of plane blocks as a component of multimodal analgesia has been increased. ESPB and SAPB are some of them. In addition, SAPB application is increasing in patients who underwent thoracotomy and VATS. There is no consensus on the dose of analgesia in these studies. There are studies on volumes between 10 ml and 40 ml in the literature. In this study, it was aimed to compare the volumes of 20 ml and 30 ml containing local anesthetic at the same concentration (0.25% bupivacaine) of SAPB block to be performed with USG in patients who underwent VATS.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: May 15, 2024
• Est. primary completion date: April 15, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• 18 to 65 years old

• ASA physical status I-II-III

• BMI 18 to 30 kg/m2

• Elective video assisted thoracoscopic surgery

Exclusion Criteria:

• Patient refusing the procedure

• Emergency surgery

• Chronic opioid or analgesic use

Related Conditions & MeSH terms

• Local Anesthetic
• Pain, Postoperative
• Serratus Anterior Plane Block
• Thoracic Surgery, Video-Assisted

Intervention

Procedure:
• Serratus Anterior Plan Block with 20 ml
Superficial serratus anterior plane block with 20 ml will be applied to the patients under real-time ultrasound guidance.
• Serratus Anterior Plan Block with 30 ml
Superficial serratus anterior plane block with 30 ml will be applied to the patients under real-time ultrasound guidance.

Locations

Country	Name	City	State
Turkey	Ankara Atatürk Chest Disease and Chest Surgery Training and Research Hospital	Kecioren	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain Scores	Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 1st, 2nd, 4th, 8th, 16th, 24th and 48th hours after surgery.	48 hours after surgery
Secondary	Morphine Consumption	Morphine consumption for 24 hours will be recorded	24 hours after surgery