Comparison of Quadratus Lumborum Intramuscular and Transmuscular in Postoperative Pain

Pain, Postoperative Clinical Trial

Official title:

Comparison of the Effectiveness of Intramuscular and Transmucular Quadratus Lumborum Blocks Quality in Postoperative Pain

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05005871
• Other study ID #: UNUD-CTR-FK150621-001
• Status: Completed
• Phase: N/A
• Start date: September 1, 2021
• Est. completion date: October 14, 2021

Study information

• Verified date: October 2021
• Source: Udayana University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Acute pain is reported in approximately 80% of patients undergoing postoperative care for various types of surgical procedures in the United States. Another study reported patient postoperative pain intensity with 75% with severe pain in the first 1 to 2 postoperative days and 38% reporting moderate to severe pain at 14 postoperative days. Several modalities have been used as the standard for the management of pain postoperative C-sections.

One of the postoperative analgesic modalities for SC is quadratus lumborum block (QLB). This technique has advantages in relieving postoperative pain after C-section because it is considered to be able to relieve visceral pain as well as somatic pain. The transmuscular QLB (QLBT) approach is one of the most frequently used. This technique was found to be effective with regard to the distribution of analgesics to the paravertebral spaces which is the hallmark of QLB. However, this technique was found to be difficult to perform. Difficulties were reported related to the position of the procedure i.e. lateral or sitting position.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 48
• Est. completion date: October 14, 2021
• Est. primary completion date: September 30, 2021
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Underwent C-section with subarachnoid block

• Aged 18-35 years old.

• ASA preoperative physical status 1-2

Exclusion Criteria:

• Coagulopathy

• Anatomic abnormalities of the abdomen

• History of allergy to local anesthesia

• History of hyperalgesia

• History of drug abuse (sedatives, opioids, paracetamol, or other pain relievers)

• Require postoperative intensive care

• Refuse to participate in research.

Related Conditions & MeSH terms

• Acute Pain
• Cesarean Section Complications
• Pain, Acute
• Pain, Postoperative

Intervention

Other:
• Quadratus lumborum block after C-section surgery as postoperative pain management
To manage postoperative pain, the subjects will be allocated to either QLB or QLTB group to receive the respective intervention.

Locations

Country	Name	City	State
Indonesia	Sanglah General Hospital	Denpasar	Bali

Sponsors (1)

Lead Sponsor	Collaborator
Udayana University

Country where clinical trial is conducted

Indonesia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Postoperative pain	Postoperative pain intensity measured by Visual Analog Scale (VAS), 0=no pain, 100=worst pain	Up to 24 hours after surgery
Primary	Postoperative morphine requirements	Total delivered morphine dose after surgery to alleviate postoperative pain (measured by total delivered dose recorded on the Patient-Controlled Analgesia tool)	Up to 72 hours after surgery