Pain, Postoperative Clinical Trial
Official title:
Effect of Dexmedetomidine as an Adjuvant to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block Versus Caudal Block for Post-operative Analgesia in Children Undergoing Congenital Inguinal Hernia Repair
This study compares the efficacy of Dexmedetomidine as an adjuvant to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block versus Caudal Block for post-operative analgesia in children undergoing congenital inguinal hernia repair especially to provide prolonged post-operative analgesia and decrease opioid consumption.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | October 30, 2021 |
Est. primary completion date | October 25, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 2 Years to 12 Years |
Eligibility | Inclusion Criteria: - age 2-12 years - Elective congenital inguinal hernia repair operation under general anaesthesia. - Physical Status: ASA I and II Patients after taking written and informed consent from the parents or care giver. Exclusion Criteria: - Refusal of procedure or participation in the study by parents. - Physical status: ASA III or above. - Children undergoing bilateral lower abdominal surgeries. - Infection at site of injection. - Congenital anomaly of the spine. - History of developmental delay, neurological disease, skeletal deformities. - History or evidence of coagulopathy. - Allergies to drugs used (Bupivacaine 0.5%)( dexmedetomidine/prcedex) |
Country | Name | City | State |
---|---|---|---|
Egypt | AinShams Hospitals | Cairo |
Lead Sponsor | Collaborator |
---|---|
Ain Shams University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | When Dexmedetomidine is administered in combination with local anesthetics in the epidural space, it has been shown to reduce postoperative analgesic requirements and have a significantly analgesic effect" | The primary outcome measures were the time to first analgesia (in minutes from the time of caudal (or) TAP block injection to first registration of modified VAS scale =3 at any point of time will receive paracetamol 10mg/kg orally | Within 24 hours post operative |
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