Timing for Removal of Chest Tubes in Adult Cardiac Surgery

Pain, Postoperative Clinical Trial

Official title: Timing for Removal of Chest Tubes in Adult Cardiac Surgery

Status Terminated

Clinical Trial Summary

Rationale:

Evidence regarding the timing of chest tube removal after cardiac surgery is sparse. The timing of chest tubes removal constitutes a balancing act between risk of retained blood syndrome, infection, patient discomfort and opioid-related side effects. Several studies have shown that chest tubes can safely be removed on the first postoperative day compared to later. A single retrospective study raised concern as chest tube removal on the day of surgery was associated with an increased requirement of drainage of pleural effusions.

Primary Objective:

To compare the impact of two standard chest tube removal protocols following open-heart surgery on the incidence of pleural and/or pericardial effusion requiring invasive drainage

Secondary Objectives

To evaluate the impact of chest tube removal on the day of surgery (DAY0) compared to the first postoperative day (DAY1) regarding:

• Comsumption of analgetic drugs

• Early postoperative pain

• Incidence of infection

• Early postoperative respiratory function

Study design:

Single-center, open, parallel-group, prospective, cluster-randomized controlled trial Alternate assignment of chest tube removal according to Day 0 versus Day 1 protocol based upon the month of surgery (even versus odd months).

Study population:

1300 consecutive patients undergoing elective open heart surgery in full or lower hemisternotomy with or without cardiopulmonary bypass including coronary artery bypass grafting, valve surgery, simple aortic surgery or combinations.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Chest Tube
• Effusion Pleural
• Heart Surgery
• Pain, Postoperative

• NCT number: NCT04487262
• Study type: Interventional
• Source: Aarhus University Hospital Skejby
• Status: Terminated
• Phase: N/A
• Start date: September 1, 2020
• Completion date: October 31, 2021