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Dexketoprofen and Etoricoxib in Patients Undergoing Hip Arthroplasty — etoketo  

Pain, Postoperative Clinical Trial

Official title:
The Central Nervous Penetration of Dexketoprofen and Etoricoxib and Their Effect on Pain and Inflammatory Reaction in Patients Undergoing Hip Arthroplasty

Clinical Trial Summary

The main purpose of this study was to determine the plasma and central nervious system pharmacokinetics of dexketoprofen and etoricoxib. The secondary aim was to asses their effect on the concentrations of interleukin 6, prostaglandin E2 and other proinflammatory markers both in plasma and cerebrospinal fluid. Thirdly, the investigators aimed to evaluate their efficacy in postoperative pain treatment.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02568735
Study type Interventional
Source Kuopio University Hospital
Contact
Status Completed
Phase Phase 4
Start date January 2013
Completion date December 2014
View Details
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