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Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous Ibuprofen

Pain, Postoperative Clinical Trial

Clinical Trial Summary

Postoperative hyperalgesia has been reported after intraoperative administration of small or high-dose remifentanil. Cyclooxygenase inhibitor exhibit preventive effects on the development of opioid-induced hyperalgesia. The aim of this study is to evaluate the preventive effect of intravenous ibuprofen (Caldolor®) on remifentanil-induced hyperalgesia

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02243254
Study type Interventional
Source Seoul National University Hospital
Contact
Status Completed
Phase N/A
Start date July 2014
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