Pain, Postoperative Clinical Trial
Official title:
Ultrasound Guided Nerve Block Combinations for Anterior Cruciate Ligament Reconstruction; Femoral, Saphenous and Obturator (Posterior Branch)Nerves.
Anterior cruciate ligament reconstruction is a routine surgical procedure. Traditional
femoral/sciatic block combinations effectively reduce postoperative pain, but results in
considerable motor blockade. The investigators aimed to evaluate postoperative pain relief
and the degree of motor block with block combinations of femoral nerve (FEM) and obturator
[posterior branch] nerve (ONP), versus saphenous nerve (SAPH) and ONP, versus placebo blocks
with isotonic saline. All patients received standard patient controlled analgesia with
morphine.Randomized, placebo-controlled and double-blinded clinical trial. Following IRB
approval, 81 patients were planned to be randomized to one of three USG block combinations:
Active FEM+ONP, active SAPH+ONP or no active blocks (sham blocks) Ropivacaine 0.75% was used
for all active blocks following induction of general anaesthesia [propofol-remifentanil,
laryngeal mask airway]. Primary outcome measure: Localized PACU pain scores (AUC) 0-6 hours
postoperatively at rest.
Secondary outcome measures: Opioid consumption, opioid related side effects, PACU time,
motor abilities of daily living scores [modified Barthel/100 index], perceived ill health
[Short form-8] scores and degree of motor blockade [Jensen- Børglum motor test].
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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