Pain, Postoperative Clinical Trial
Official title:
The Scalp Block for Postoperative Pain Control in Craniosynostosis Surgery: a Case Control Study
Postoperative analgesia after corrective surgery of paediatric craniosynostosis is crucial in term of short and long-term outcomes. The objective of this observational case- control study was to evaluate the effectiveness of an analgesic technique based on the scalp block versus traditional pharmacological approach.
Several studies on craniosynostosis and the correlated risk factors have been published, the
majority of them focusing on the perioperative management of blood losses and avoidance of
haemorrhagic shock. Other issues related to anaesthetic management of the surgical correction
of craniosynostosis are metabolic and electrolyte disturbances.
Even if craniosynostosis surgery is an invasive procedure, there is a current misconception
that it would be associated with minimal pain, despite the extensive exhibition of the skull
and periostea dissection. The Literature about the assessment and management of postoperative
pain in this particular surgical setting is scarce. Assessment of pain in infants is
challenging, and often relies on clinical observation. To date, there are no evaluative and
therapeutic parameters globally accredited in this category of patients. The scalp nerve
block (SNB) is a regional anaesthetic technique, performed since several years in children
undergoing a variety of procedures, from neurosurgery to eye-nose-throat surgery.SNB has been
proposed as a complement to the routine craniosynostosis anaesthetic protocol, and should be
associated to a reduced need for opioids.
Thirteen patients, aged between 3 months and 2 years, undergoing cranioplasty for the
correction of craniosynostosis were subjected to SNB (Group SB) with Levobupivacaine 0.125%
(total dose 2 mg/kg), performed before awakening, in combination with intraoperative
intravenous acetaminophen (15 mg/kg if body weight >10Kg, 7 mg/kg if body weight < 10 kg).
The SNB procedure was performed using the modified Pinosky technique, with levobupivacaine
0,125%(10). A targeted infiltration of 0,75-2ml of local anaesthetic (LA) solution was done
at multiple sites with a 23G needle.
This Group of patients were compared with another group of 13 patients, derived from our
database, and treated with the traditional pharmacological approach given intraoperatively
(intravenous acetaminophen according to the body weight, plus intravenous tramadol 1 mg/kg).
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05480111 -
The Role of Quadratus Lumborum Blocks Following Minimally Invasive Hysterectomy
|
Phase 4 | |
| Completed |
NCT06129305 -
Erector Spina Muscle Distance From the Skin at Different Thoracal Elevations
|
||
| Completed |
NCT04401826 -
Micro-surgical Treatment of Gummy Smile
|
N/A | |
| Recruiting |
NCT04020133 -
the Role of Popliteal Plexus Block in Pain Management After Anterior Cruciate Ligament Reconstruction.
|
N/A | |
| Completed |
NCT03023462 -
Efficacy of an Anterior Quadratus Lumborum Block vs. a TAP-block for Inguinal Hernia Repair
|
N/A | |
| Completed |
NCT03652103 -
Efficiency of Erector Spinae Plane Block For Patients Undergoing Percutaneous Nephrolithotomy
|
Phase 4 | |
| Completed |
NCT03546738 -
Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery
|
N/A | |
| Withdrawn |
NCT03528343 -
Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy
|
Phase 1/Phase 2 | |
| Terminated |
NCT03261193 -
ITM + Bupivacaine QLB vs. ITM + Sham Saline QLB for Cesarean Delivery Pain
|
Phase 3 | |
| Completed |
NCT02525133 -
Phase 3 Study of Efficacy and Safety of the XaraColl® Bupivacaine Implant After Hernioplasty
|
Phase 3 | |
| Completed |
NCT03244540 -
Regional Analgesia After Cesarean Section
|
Phase 4 | |
| Enrolling by invitation |
NCT05316168 -
Post Operative Pain Management for ACL Reconstruction
|
Phase 3 | |
| Recruiting |
NCT04130464 -
Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
|
Phase 4 | |
| Enrolling by invitation |
NCT04574791 -
Addition of Muscle Relaxants in a Multimodal Analgesic Regimen for Analgesia After Primary Total Knee Arthroplasty
|
N/A | |
| Completed |
NCT04073069 -
Scalp Infiltration With Diprospan Plus Ropivacaine for Postoperative Pain After Craniotomy in Adults
|
Phase 4 | |
| Completed |
NCT04526236 -
Influence of Aging on Perioperative Methadone Dosing
|
Phase 4 | |
| Recruiting |
NCT05351229 -
Intrathecal Morphine for Analgesia in Video-assisted Thoracic Surgery
|
Phase 4 | |
| Enrolling by invitation |
NCT05543109 -
Ultrasound Guided Psoas Compartment Block vs Suprainguinal Fascia Iliaca Compartment Block
|
N/A | |
| Completed |
NCT05346588 -
THRIVE Feasibility Trial
|
Phase 3 | |
| Completed |
NCT04919317 -
Combination Dexamethasone and Bupivacaine Pain Control in Reduction Mammaplasty
|
Phase 2 |