Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery

Pain Management Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02841982
• Other study ID #: cuixulei3
• Status: Completed
• Phase: N/A
• Start date: August 2016
• Est. completion date: December 2018

Study information

• Verified date: May 2019
• Source: Peking Union Medical College Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay and incidence of chronic pain,et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic renal surgeries.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: December 2018
• Est. primary completion date: November 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 17 Years to 80 Years

Eligibility

Inclusion Criteria:

• Age 18-70 yrs

• American Society of Anesthesiologists physical status?-?

• Undergo laparoscopic nephrectomy

• Informed consent

Exclusion Criteria:

• A known allergy to the drugs being used

• Coagulopathy, on anticoagulants

• Analgesics intake, history of substance abuse

• Participating in the investigation of another experimental agent

• Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)

Related Conditions & MeSH terms

• Laparoscopic Renal Surgery
• Nerve Block
• Pain Management

Intervention

Procedure:
• single-injection QLB(quadratus lumborum block)
Inject local anesthetics in between quadratus lumborum and psoas major without continuous local infusion

Device:
• Philip CX50 Ultrasound Scanner
The curved (C1-5) probe of Philip CX 50 Ultrasound Scanner is used for scan
• PAJUNK StimuLong

Drug:
• single dose ropivacaine
0.6ml/kg 0.5% ropivacaine with 1:200,000 adrenaline. given immediately after the correct position of the tip of the needle has been verified.
• Morphine given as IPCA(intravenous patient controlled analgesia)
bolus: 1.5~2mg, lock time: 10min, 1h limitation: 6~8mg

Locations

Country	Name	City	State
China	Xulei CUI	Beijing	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Cui Xulei

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	cumulative morphine consumption		within 48 postoperative hours
Secondary	The pain scores determined by the numeric rating scale (NRS, 0-10)		At 0, 2,4, 8, 12, 24 ,48,72hours after the surgery
Secondary	nausea and vomiting score		within 24 hours after the surgery
Secondary	pruritus score		within 24hour after the surgery
Secondary	ambulation time		within the 7 days after surgery
Secondary	time of recovery of bowl movement		within the 5 days after surgery
Secondary	quality of recovery	use the self-assessment 15 item QoR scale to assess the patient's recovery	3days and 5days after surgery
Secondary	Postoperative hospital length of stay		Up to 6 weeks
Secondary	patient satisfaction with anesthesia	use the Chinese version Bauer questionnaire to assess the patient satisfaction with anesthesia	48 hours after surgery