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Oxygen Delivery clinical trials

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NCT ID: NCT05699005 Recruiting - Anemia Clinical Trials

Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMO

ICONE
Start date: September 18, 2023
Phase: Phase 1
Study type: Interventional

This multicenter randomized controlled trial compare two transfusion strategies of red blood cells transfusion in patients supported by veno-arterial extracorporeal membrane oxygenation for refractory cardiogenic shock. An individualized transfusion strategy based on ScVO2 level, is compared to a conventionnal strategy based on predefined hemoglobin threshold. The primary endpoint is the consumption of packed red blod cells, secondary endpoints are subgroup analysis, mortality, morbidity, and cost-effectiveness