Oxygen Deficiency Clinical Trial
Official title:
The Effectiveness of Preoxygenation and Apneic Oxygenation Using High-flow Nasal Cannula for Pediatric Anesthetic Induction: a Prospective Randomized Open-label Clinical Trial
Endotracheal intubation in infants often involves more than one attempt, and oxygen desaturation is common. It is unclear whether nasal high-flow therapy, which extends the time to desaturation during elective intubation in infants receiving general anesthesia, can decrease the occurence of desaturation during intubation. The investigators tested the hypothesis that high-flow nasal oxygen cannulae would be effective in maintaining oxygen saturation during intubation than facemasks for pre-oxygenation. The investigators randomly allocated 84 patients undergoing elective surgery aged <=12 months to pre-oxygenation using either high-flow nasal oxygen or facemask.
Status | Not yet recruiting |
Enrollment | 84 |
Est. completion date | December 31, 2023 |
Est. primary completion date | December 31, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 1 Month to 12 Months |
Eligibility | Inclusion Criteria: - Infants undergoing general anesthesia with endotracheal intubation. Exclusion Criteria: - infants who diagnosed as cardiorespiratory problem preoperatively. |
Country | Name | City | State |
---|---|---|---|
Korea, Republic of | Seoul national university hospital | Seoul |
Lead Sponsor | Collaborator |
---|---|
Seoul National University Hospital |
Korea, Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Occurrence of oxygen desaturation <95% | from induction of anesthesia to 1 minutes after intubation, about 10 minutes. | ||
Secondary | Occurrence of oxygen desaturation <90% | from induction of anesthesia to 1 minutes after intubation, about 10 minutes. | ||
Secondary | the lowest oxygen saturation | from induction of anesthesia to 1 minutes after intubation, about 10 minutes. | ||
Secondary | the changes in oxygen reserve index | from induction of anesthesia to 1 minutes after intubation, about 10 minutes. | ||
Secondary | ETCO2 in first breath after intubation | from induction of anesthesia to 1 minutes after intubation, about 10 minutes. | ||
Secondary | ETO2 in first breath after intubation | from induction of anesthesia to 1 minutes after intubation, about 10 minutes. | ||
Secondary | Number of intubation attempts | from induction of anesthesia to 1 minutes after intubation, about 10 minutes. | ||
Secondary | Intubation times | time required to securing the airway. | from induction of anesthesia to 1 minutes after intubation, about 10 minutes. | |
Secondary | Occurrence of rescue bag mask ventilation | from induction of anesthesia to 1 minutes after intubation, about 10 minutes. | ||
Secondary | Occurrence of gastric insufflation | from induction of anesthesia to 1 minutes after intubation, about 10 minutes. |
Status | Clinical Trial | Phase | |
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