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Short-term Health Benefits of Using Fresh Air Filtration System in Classroom

Oxidative Stress Clinical Trial

Official title:
Effects of Fresh Air Filtration System on Indoor Air Quality and Children's Health in Shanghai Schools

Clinical Trial Summary

A randomized crossover trial will be conducted in 90 primary school children in 3 classrooms in Shanghai, China. The effects of fresh air ventilation/filtration system, fresh air ventilation system with no filtration and natual ventilation will be compared on the effects of reducing indoor PM2.5 and chilhood health. Biological samples of children are going to be collected to investigate the associations between indoor air pollution and biomarkes of certain health effects.

Clinical Trial Description

A randomized crossover trial among 90 primary students in 3 classrooms in Shanghai, China will be performed. Three arms are going to be 1) fresh air filtration system, 2) fresh air system with no filtration and 3) natural ventilation. Each arm is going to be in use for five continuous weekdays followed by one week of wash-out. After one-week of wash out, a cross over change between 3 arms is going to be taked. Then the 2nd week of intervention is performed followed by the 2nd wash-out week. The same cross-over change between 3 arms is going to be repeated again until each classroom will be applied by all three arms of ventilation. A total of 5 weeks is required for the project. Children's biological samples including saliva, urine and skin samples will be collected as well as exhaled NO. A questionnaire on children's perception on air quality will be assessed as well. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03788330
Study type Interventional
Source Fudan University
Contact
Status Completed
Phase N/A
Start date December 7, 2018
Completion date January 22, 2019
View Details
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