Clinical Trials Logo
  1. Home
  2. Oxidative Stress
  3. NCT00721643
  4. Details
NCT00721643 Clinical Trial

Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)

Oxidative Stress Clinical Trial

Official title:
Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00721643
Other study ID # HNRCA2580
Secondary ID BioGreen 2007030
Status Completed
Phase Early Phase 1
First received July 22, 2008
Last updated April 24, 2017
Start date July 2008
Est. completion date December 2010

Study information
Verified date April 2017
Source Tufts University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The absorption kinetics of polyphenols in angel's plant (Angelica keiskei), which is a dark green leafy vegetable rich in antioxidant nutrients, will be determined in older adults in this pilot study.

Recruitment information / eligibility
Status Completed
Enrollment 10
Est. completion date December 2010
Est. primary completion date March 2009
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 60 Years and older
Eligibility Inclusion Criteria:

- Healthy subjects (>60 yr, n=5)

- subjects with metabolic syndrome (>60 yr, n=5)

- Subjects who has

- high fasting plasma glucose (>5.6 mmol/L),

- central obesity (waist-hip ratio, >0.9 for men, >0.85 for women)

- either high blood pressure (>130/85 mmHg) or high triacylglycerol (>1.7 mmol/L) will be selected to have metabolic syndrome.

- normal hematological parameters, normal serum albumin, normal liver function, and normal kidney function

- no history of smoking or alcoholism.

Exclusion Criteria:

- consume >7 alcoholic drinks/wk

- taking cholesterol medication or hormone replacement

Study Design

Related Conditions & MeSH terms

Intervention

Dietary Supplement:
• angel's plant (Angelica keiskei)
Healthy control, one time dose of 5g dry power of Angelica keiskei
• Angel's plant (Angelica keiskei)
Metaboic syndrome subjects, one time dose of 5g dry powder of angel's plant (Angelica keiskei)

Locations
Country Name City State
United States Jean Mayer USDA-Human Nutrition Research Center on Aging at Tufts University Boston Massachusetts

Sponsors (1)
Lead Sponsor Collaborator
Tufts University

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Plasma quercetin 0, 30, 60, 100, 180, 240, 300, 360, 420 & 480 min
See also
  Status Clinical Trial Phase
Completed NCT03255187 - Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution N/A
Completed NCT04136821 - The Long-term Effects of Oceanix™ on Resistance Training Adaptations N/A
Recruiting NCT03790345 - Vitamin B6 and B12 in the Treatment of Movement Disorders Induced by Antipsychotics Phase 2/Phase 3
Completed NCT03358524 - Effects of Vitamin E Supplementation on Free Radicals and Fat Level of Obese Adolescence in Jakarta, Indonesia Phase 4
Recruiting NCT05327348 - Effectiveness of IV Vitamin C in Reducing Oxidative Stress Associated With Free Flap Surgery Phase 3
Completed NCT03288623 - The Effects of Dark Chocolate Implementation in Elite Athletes N/A
Completed NCT04419025 - Efficacy of N-Acetylcysteine (NAC) in Preventing COVID-19 From Progressing to Severe Disease Phase 2
Completed NCT04597983 - Effect of 8-week Intake of 2S-hesperidin on Performance, Body Composition and Biochemicals Markers in Amateur Cyclists N/A
Not yet recruiting NCT06159543 - The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes N/A
Enrolling by invitation NCT03030456 - Whole Body Vibrations on Functional Capacity, Muscular Strength, and Biochemical Profile in Elders N/A
Completed NCT02256254 - SIMOX - Induction of Oxidative Stress Phase 2
Not yet recruiting NCT02202239 - Effect of Induction and Maintenance of Anesthesia With Etomidate on Hemodynamics and Oxidative Stress in Diabetic Patients Phase 4
Recruiting NCT02048592 - Impact of Immunonutrition on the Patients With Cystic Fibrosis Phase 4
Completed NCT01942460 - Ferumoxytol for Iron-Deficiency Anemia in Chronic Kidney Disease and Peritoneal Dialysis Patients Phase 4
Completed NCT02463318 - The Effect of Melatonin on Gene Expression and Activity of the Sirt1 and Its Target Genes Catalase and MnSOD in Multiple Sclerosis Patients and Healthy Subjects N/A
Completed NCT02177383 - Action of Essential Fatty Acids on the Expression of Antioxidant Genes and Athletic Performance N/A
Completed NCT01990391 - Brazil Nut Consumption in Microvascular Endothelial Function, Oxidative Stress and Metabolic Abnormalities N/A
Completed NCT00845130 - Quantitative in Vivo Biomarkers of Oxidative Stress in Diabetes N/A
Completed NCT00607893 - Efficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea N/A
Active, not recruiting NCT00247507 - The Effects of Acetylcysteine on Alleviating Damage of Oxidative Stress in Hemodialysis Patients Phase 4