Effects of High Protein Intake With Intense Exercise and Energy Deficit

Overweight Clinical Trial

— RIPPED  

Official title:

Effects of High Protein Intake With Intense Exercise and Energy Deficit

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01776359
• Other study ID #: REB 12-670
• Status: Completed
• Phase: N/A
• First received: January 14, 2013
• Last updated: June 6, 2015
• Start date: February 2013
• Est. completion date: December 2014

Study information

• Verified date: June 2015
• Source: McMaster University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: Hamilton Health Sciences
• Study type: Interventional

Clinical Trial Summary

A four week intervention will take place with the participants. They will undergo 6 days a week of high intensity training. They will also be at a 40% energy deficiency. One group will have a normal intake of protein, 1.2g/kg, while the other will have 2.4g/kg. It is our thesis that the participants with the higher protein will retain more lean mass.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: December 2014
• Est. primary completion date: July 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• 18-30 males

• Healthy

Exclusion Criteria:

• more than 15% body fat

• 35-50ml/kg/min VO2

• BMI grater than 27

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Overweight

Intervention

Dietary Supplement:
• High Protein
2.4g/kg of protein
• Low Protein
1.2g/kg of protein

Locations

Country	Name	City	State
Canada	McMaster University	Hamilton	Ontario

Sponsors (1)

Lead Sponsor	Collaborator
McMaster University

Country where clinical trial is conducted

Canada, 

References & Publications (3)

Butterfield GE, Calloway DH. Physical activity improves protein utilization in young men. Br J Nutr. 1984 Mar;51(2):171-84. — View Citation

Demling RH, DeSanti L. Effect of a hypocaloric diet, increased protein intake and resistance training on lean mass gains and fat mass loss in overweight police officers. Ann Nutr Metab. 2000;44(1):21-9. — View Citation

Mettler S, Mitchell N, Tipton KD. Increased protein intake reduces lean body mass loss during weight loss in athletes. Med Sci Sports Exerc. 2010 Feb;42(2):326-37. doi: 10.1249/MSS.0b013e3181b2ef8e. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Body Composition	To compare the effect of normal protein intake (1.2 g/kg per day) and increased protein intake (2.4 g/kg per day) on body composition over a 4 week period of energy restriction in young males (18-30), with intense exercise training. Body composition will be measured via DXA, Bod Pod, Bio-impedance, skin folds.	4 weeks	No
Secondary	Psychological state	To compare the psychological state of the participants, before, during and after the intervention. To see if the mind will grow with the body as high intensity exercise is performed, or whether the mind will tire and scores will be reduced. Measurement tactics will in include POMS, and PANAS questionnaires for mood, and stroop, isometric hand grip, operation span test, and vigilance task.	4 weeks	No