SubsTRate OxidatioN in Girls — STRONG  

Overweight Adolescents Clinical Trial

Official title: Race Differences in 24-hour Energy Expenditure, Substrate Oxidation, and Appetite in Adolescent Girls

Status Completed

Clinical Trial Summary

This study will examine race differences in total energy expenditure and respiratory quotient (RQ) during and after exercise, compared to a sedentary control condition, in adolescent girls who are classified as overweight. In addition, subjective appetite and objective energy intake will be measured throughout the assessment periods.

Clinical Trial Description

Aim 1: Measure 24-hour energy expenditure and its components (resting, activity, and sleep energy expenditure) and compare differences between African-American and White girls.

Hypothesis: Total, resting, and sleep energy expenditure will be lower in African-American relative to White girls. Activity energy expenditure will be equivalent per the study design.

Aim 2: Measure and compare substrate oxidation and associations with appetite (i.e., hunger, desire to eat) and energy intake between African-American and White girls.

Hypothesis: African-American girls will have a higher RQ at rest, during exercise, and following exercise, and RQ will be positively associated with subjective appetite ratings and energy intake. ;

Related Conditions & MeSH terms

• Overweight
• Overweight Adolescents

• NCT number: NCT04483921
• Study type: Interventional
• Source: Pennington Biomedical Research Center
• Status: Completed
• Phase: N/A
• Start date: July 15, 2020
• Completion date: October 20, 2023