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Clinical Trial Summary

To assess the impact of comprehensive staging surgery with no lymphadenectomy on survival and quality of life in patients with early-stage ovarian cancer.


Clinical Trial Description

OBJECTIVES: Compare the efficacy and safety in patients with International Federation of Gynecology and Obstetrics (FIGO) stage IA -IIA epithelial ovarian cancer, undergo completion staging surgery including systematic pelvic and para-aortic lymphadenectomy versus comprehensive staging surgery without lymphadenectomy. OUTLINE: This is a randomized phase III multicenter study. Patients will receive comprehensive staging surgery without Lymphadenectomy or completion staging surgery including systematic pelvic and para-aortic lymphadenectomy, and the adjuvant chemotherapy will accord to National Comprehensive Cancer Network (NCCN) guidelines. Patients are followed up every 3 months within the first 2 years, and then every 6 months. PROJECTED ACCRUAL: A total of 656 patients will be recruited for this study within 5 years. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04710797
Study type Interventional
Source Sun Yat-sen University
Contact Jihong Liu, Ph.D.
Phone 86-20-87343102
Email liujih@mail.sysu.edu.cn
Status Recruiting
Phase N/A
Start date January 31, 2021
Completion date December 31, 2028

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