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Use of Nafamostat Mesilate for Anticoagulation in Patients With ECMO

Extracorporeal Membrane Oxygenation Complication Clinical Trial

Official title:
Use of Nafamostat Mesilate for Anticoagulation in Patients With Extracorporeal Membrane Oxygenation After Cardiac Surgery: Efficacy and Safety

Clinical Trial Summary

The purpose of this study is to evaluate the effectiveness and safety of nafamostat mesilate compared with unfractionated heparin for anticoagulation in patients with ECMO after cardiac surgery.

Clinical Trial Description

Selecting patients who require systemic anticoagulation as the study subjects from patients undergoing extracorporeal membrane oxygenation assistance after cardiac surgery. Randomly divided into the nafamostat mesilate group and unfractionated heparin group. To evaluate the efficacy and safety of nafamostat mesilate by comparing the incidence of bleeding and thrombosis within the target anticoagulant level range between two groups of patients during ECMO ;

Study Design

Related Conditions & MeSH terms

  • Extracorporeal Membrane Oxygenation Complication
Clinical Trial Details
NCT number NCT06276010
Study type Interventional
Source Beijing Anzhen Hospital
Contact Xiaotong Hou, MD
Phone 010-64456631
Email xt.hou@ccmu.edu.cn
Status Not yet recruiting
Phase N/A
Start date March 1, 2024
Completion date December 31, 2026
View Details
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