Anterior Cruciate Ligament Rupture Clinical Trial
Official title:
"Valutazione Dell'Epidemiologia e Dei Risultati Clinici Nel Trattamento Artroscopico Delle Lesioni Del Legamento Crociato Anteriore"
This retrospective, prospective observational study aims to evaluate the epidemiology and rate of anterior cruciate ligament re- rupture after surgery in patients treated from January 2020 to December 2030 by recording both clinically and radiographically ligament reconstruction. The primary outcome is the rate of rupture of the anterior cruciate ligament as measured by the Lachmann test in which a positive value for re-rupture is an anterior translation of the tibia greater than 10mm relative to the femur Secondary Objectives: Verify predisposing factors to anterior cruciate ligament injuries (so anatomical factors such as tibial slope, trochlear groove), demographic factors (age, sex, weight, sports played), and the rate of return to sports, quality of life via questionnaires, and arthrosis at the operated knee
| Status | Recruiting |
| Enrollment | 370 |
| Est. completion date | December 31, 2030 |
| Est. primary completion date | December 31, 2030 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years to 65 Years |
| Eligibility | Inclusion Criteria: - - Males and females- attained skeletal maturity - 18-65 inclusive - Patients operated on anterior cruciate ligament reconstruction surgery at the Hospital's Casco unit from 2010 to 2030 - Signature informed consent for patients who will be operated on in the prospective phase (from CE approval date to 2030) Exclusion Criteria: - failure to reach skeletal maturity - Concomitant ligamentous injuries (pcl, mcl, lcl) - Neuropsychiatric illness, developmental disorders - Pregnant women through self-declaration or breastfeeding - Minors |
| Country | Name | City | State |
|---|---|---|---|
| Italy | IRCCS Istituto Ortopedico Galeazzi | Milano |
| Lead Sponsor | Collaborator |
|---|---|
| Istituto Ortopedico Galeazzi |
Italy,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Rerupture rate | rate of rerupture rare evaluated with anterior tibial translation | 10 years |
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05487768 -
Functional Connectivity After Anterior Cruciate Ligament Reconstruction
|
N/A | |
| Recruiting |
NCT04390035 -
BFRT in Adolescents After ACL Reconstruction
|
N/A | |
| Recruiting |
NCT02740452 -
Anterior Cruciate Ligament Rupture
|
N/A | |
| Not yet recruiting |
NCT02555917 -
Comparison of Remnant Preserving Versus Remnant Resecting Anterior Cruciate Ligament Reconstruction
|
N/A | |
| Active, not recruiting |
NCT00529958 -
Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction
|
N/A | |
| Completed |
NCT05109871 -
Reliability and Validity of Inline Dynamometry Study for Measuring Knee Extensor Torque
|
N/A | |
| Not yet recruiting |
NCT06048848 -
FNB in ACL Recon Under GA
|
N/A | |
| Not yet recruiting |
NCT06048874 -
FNB in ACL Recon Under SA
|
N/A | |
| Terminated |
NCT03529552 -
Evaluation After Reconstruction of the Anterior Cruciate Ligament of the Knee Using the Bioresorbable Interference Screw (SMS): Resorbability, Per- and Post-operative Complications and Articular Functional Recovery.
|
N/A | |
| Completed |
NCT04285853 -
Are Opioids Needed After ACL Reconstruction
|
Phase 4 | |
| Recruiting |
NCT04088227 -
Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears
|
Phase 2 | |
| Active, not recruiting |
NCT03671421 -
Number One Overall Graft Pick? Hamstring vs Bone-Patellar-Tendon-Bone vs Quadriceps Tendon
|
N/A | |
| Not yet recruiting |
NCT04957706 -
Diagnostic Study of ACL Rupture With Anterior Drawer Test at 90° of Hip Flexion
|
||
| Not yet recruiting |
NCT04953676 -
A Clinical Trial of the Round-tunnel and Flat-tunnel Technique of ACL Reconstruction
|
N/A | |
| Enrolling by invitation |
NCT03365908 -
Pain Management of ACL Reconstruction
|
N/A | |
| Recruiting |
NCT06030791 -
BTB Graft Harvest and Donor Site Morbidity After ACL Reconstruction
|
||
| Recruiting |
NCT03950024 -
Improvement of Knowledge About the Arthrogenic Muscle Inhibition in the Aftermath of Knee Trauma.
|
N/A | |
| Recruiting |
NCT03229369 -
Association of ALL and ACL Reconstruction Versus Isolated ACL Reconstruction in High-risk Population: a RCT.
|
N/A | |
| Completed |
NCT01267435 -
Evaluation of Tibial and Femoral Tunnel Position After Arthroscopic Reconstruction of the Anterior Cruciate Ligament
|
Phase 2 | |
| Recruiting |
NCT06430775 -
Exploring Prolonged AMR in ACL Reconstructed Patients
|