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Quantitative Computed Tomography for Mortality Risk Stratification in ARDS — CT4ARDS-2  

Acute Respiratory Distress Syndrome Clinical Trial

Official title:
Quantitative Computed Tomography for Mortality Risk Stratification in ARDS

Clinical Trial Summary

Acute respiratory distress syndrome remains a deadly disease with hospital mortality remaining between 40 to 50%. ARDS mortality risk factors have been identified from patient history, common clinical and biological variables in the lung SAFE study. Part of ARDS mortality is attributable to ventilator-induced lung injury (VILI), in relation with inappropriate settings on the ventilator. Tidal hyperinflation and recruitment/derecruitment during lung inflation are 2 identified mechanisms leading to VILI, that may be identified on computed tomography while poorly identified with variables collected at the bedside. The aim of this study is to identify whether tidal hyperinflation identified on computed tomography is a risk factor for ARDS mortality, independently from know bio-clinical risk factors.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06113276
Study type Observational
Source Hospices Civils de Lyon
Contact
Status Recruiting
Phase
Start date November 6, 2020
Completion date May 1, 2025
View Details
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