Disseminated Intravascular Coagulation Clinical Trial
Official title:
The Proactive Diagnostic Value of Hemostatic Biomarkers in Disseminated Intravascular Coagulation
The project was undertaking by Qilu Hospital of Shandong University, aiming to evaluate diagnostic performance of hemostatic biomarkers in disseminated intravascular coagulation.
Status | Recruiting |
Enrollment | 462 |
Est. completion date | June 30, 2024 |
Est. primary completion date | December 31, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 94 Years |
Eligibility | Inclusion Criteria: - 18 years old, non-perinatal period, a hospitalization length of=3 days. Exclusion Criteria: - primary hematologic diseases, decompensated liver cirrhosis, chemotherapy history. |
Country | Name | City | State |
---|---|---|---|
China | Miao Xu | Ji'nan | Shandong |
Lead Sponsor | Collaborator |
---|---|
Qilu Hospital of Shandong University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | whether DIC occured | DIC includes pre-DIC and overt-DIC | From date of detecting hemostatic biomarkers until the date of first ISTH-DIC scores =5, assessed up to 7 days. | |
Secondary | whether death occurred | Based on the death records in the electronic medical records | From date of admission until the date of death, assessed up to 5 months |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04580563 -
Study Assessing Efficacy of Plasmatherapy in Septic Shock-induced Coagulopathy: Feasibility Study
|
N/A | |
Completed |
NCT01704001 -
Clinical Pharmacokinetics Study of ART-123 in Disseminated Intravascular Coagulation (DIC) Subjects With Renal Impairment
|
Phase 4 | |
Terminated |
NCT00299949 -
Thrombin Generation and Thromboelastography in Non-overt DIC
|
N/A | |
Recruiting |
NCT03577015 -
International Prospective Registry of Disseminated Intravascular Coagulation
|
||
Withdrawn |
NCT04363840 -
The LEAD COVID-19 Trial: Low-risk, Early Aspirin and Vitamin D to Reduce COVID-19 Hospitalizations
|
Phase 2 | |
Completed |
NCT04873349 -
Standardized Olive Leaf Capsules; as a Co-therapy in the Treatment of COVID-19 Patients
|
N/A | |
Withdrawn |
NCT01090115 -
Study to Look at the Effects of ART-123 on Patients With Sepsis and Disseminated Intravascular Coagulation (DIC)
|
Phase 2 | |
Active, not recruiting |
NCT04107402 -
PLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic Shock
|
N/A | |
Terminated |
NCT00506519 -
Recombinant Human Antithrombin (ATryn®) in the Treatment of Patients With DIC Associated With Severe Sepsis
|
Phase 2 | |
Completed |
NCT00487656 -
Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation
|
Phase 2 | |
Completed |
NCT03714048 -
Blood Management During ECMO for Cardiac Support
|
||
Completed |
NCT04547153 -
Infusional Fluorouracil and Weekly Docetaxel for Gastric Cancer With Bone Marrow Involvement and DIC
|
Phase 2 | |
Completed |
NCT04460664 -
Coagulation Changes Associated With COVID-19 Infection
|
||
Completed |
NCT04356950 -
Analysis of the Coagulopathy Developed by COVID-19 Infected Patients
|
||
Completed |
NCT04356144 -
Thrombomodulin-modified Thrombin Generation Assay (TGA-TM) in Patients With Critical Infections
|
||
Recruiting |
NCT06363149 -
Disseminated Intravascular Coagulation (DIC) Score and Organ Dysfunction in Septic Shock Patients
|
||
Recruiting |
NCT02654561 -
Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation
|
Phase 3 | |
Active, not recruiting |
NCT06373159 -
An Observational Study to Learn About the Occurrence of Disseminated Intravascular Coagulation Among Adults With Sepsis in Japan
|
||
Completed |
NCT03716310 -
Platelet Reactivity in Septic Shock
|