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Clinical Trial Summary

Critically ill patients are at high risk of developing acute kidney injury (AKI). Lithium is freely filtrated at the glomerulus and almost completely reabsorbed in the proximal tubule, which provides a quantitative estimation of proximal tubule reabsorption. The investigators hypothesized that endogenous lithium reabsorption is impaired in the early stages of critical illness. Investigators would like to study 10 ICU patients with AKI diagnosed, 10 patients without AKI, and 10 healthy controls.


Clinical Trial Description

Blood and urine samples will be obtained at 08:00, 14:00 and 20:00 during one day. Renal clearance of creatinine (CCr) and lithium will be calculated. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05982340
Study type Observational
Source University Hospital of North Norway
Contact Lars Marius Ytrebø
Phone 90788058
Email lars.marius.ytrebo@unn.no
Status Recruiting
Phase
Start date August 1, 2023
Completion date December 31, 2024

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