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Clinical Trial Summary

The goal of this non-randomized prospective study is to test whether 6-weeks antibiotic treatment can cure an cardiac implantable electronic device (CIED) infection in patients where device extraction is not feasible. The main question it aims to answer: • Is 6-weeks medical therapy effective in curing definite CIED infection with device retention? Participants will discontinue the antibiotic treatment after at least 10 days iv antibiotic therapy and then per oral treatment to at least 6 weeks total. After discontinuation of antibiotics, patients are closely observed for bacterial relapse. For patients who are not interested in participation and who do not have exclusion criteria, we will ask for consent into a registry as we wish to compare patients undergoing discontinuation of antibiotics with patients undergoing standard treatment.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms

  • Cardiac Implantable Electronic Device Infection

NCT number NCT05958290
Study type Interventional
Source Rigshospitalet, Denmark
Contact
Status Recruiting
Phase N/A
Start date September 1, 2023
Completion date November 30, 2025

See also
  Status Clinical Trial Phase
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Completed NCT01043705 - TYRX™ Envelope for Prevention of Infection Following Replacement With a CRT or ICD N/A
Completed NCT05576194 - Taurolidine Containing Antimicrobial CIED Wash to Prevent Infection
Completed NCT03842124 - Improving Safety of Lead Extraction Procedures by Traction Force Sensing N/A