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Additional Consolidative Esophagectomy for the Patients With Oligometastatic Resectable ESCC — LEO  

Esophageal Squamous Cell Carcinoma Clinical Trial

Official title:
Additional Local Consolidative Esophagectomy to Traditional Systemic Therapy for Patients With Oligometastatic Resectable ESCC: A Multi-center, Open-label, Randomized Controlled Tial (LEO)

Clinical Trial Summary

At present, there are relatively clear treatment guidelines for colorectal cancer with oligometastases, while the treatment mode for resectable esophageal cancer with oligometastases is not clear and there is a lack of research results in this field. The aim of this study is to provide evidence of the optimal therapy model for the local resectable esophageal cancer with oligometastases ESCC patients, by investigating whether 2-year OS of the patients could benefit from additional local consolidative esophagectomy.

Clinical Trial Description

This study was designed as a multicenter, open-label, randomized controlled prospective clinical study. The experimental group (group A) received additional esophagectomy after 3-month systemic treatment, and the control group (group B) received only systemic treatment. 2-year OS, 3-year PFS and OS were observed in the two groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05951127
Study type Interventional
Source Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Contact
Status Active, not recruiting
Phase N/A
Start date November 1, 2022
Completion date October 31, 2027
View Details
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