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Clinical Trial Summary

To explore the effect of preoperative exercise rehabilitation on bone mineral density, tendon bone healing, change of cartilage, and gait feature in patients with anterior cruciate ligament rupture.


Clinical Trial Description

Anterior Cruciate Ligament (ACL) injury is one of the most common sports injuries. It is a serious knee injury. The fracture of ACL can cause functional instability of knee joint, damage of meniscus and articular cartilage, and even induce knee osteoarthritis and other diseases. It has great influence on knee joint and even lower limb function of patients. Arthroscopic ACL reconstruction has become the first choice in clinical treatment of ACL fracture. ACL fracture can cause local knee joint osteoporosis, and reconstruction surgery can also affect tendon bone healing, bone canal enlargement, rehabilitation period, gait, articular cartilage degradation, etc. This study intends to conduct preoperative rehabilitation intervention for young people with anterior fork rupture, and explore the effects of exercise rehabilitation on knee bone mineral density, muscle strength, proprioceptive ability and other aspects after ACL rupture, as well as the effects of knee bone mineral density, tendon bone healing, bone tunnel aperture, motor function, gait characteristics and cartilage degradation after reconstruction. ;


Study Design


Related Conditions & MeSH terms

  • Anterior Cruciate Ligament Rupture
  • Rupture

NCT number NCT05924178
Study type Interventional
Source Peking University Third Hospital
Contact Shuang Ren
Phone 17610252992
Email xixishuang123@126.com
Status Not yet recruiting
Phase N/A
Start date July 10, 2023
Completion date March 1, 2026

See also
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Recruiting NCT03950024 - Improvement of Knowledge About the Arthrogenic Muscle Inhibition in the Aftermath of Knee Trauma. N/A
Recruiting NCT03229369 - Association of ALL and ACL Reconstruction Versus Isolated ACL Reconstruction in High-risk Population: a RCT. N/A
Completed NCT01267435 - Evaluation of Tibial and Femoral Tunnel Position After Arthroscopic Reconstruction of the Anterior Cruciate Ligament Phase 2
Recruiting NCT06430775 - Exploring Prolonged AMR in ACL Reconstructed Patients