Acute Respiratory Distress Syndrome Clinical Trial
— DEBASOfficial title:
Safety of Low PEEP Maneuvers During ARDS Management
NCT number | NCT05922969 |
Other study ID # | PI2021_843_0165 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | May 28, 2022 |
Est. completion date | May 2024 |
Acute Respiratory distress syndrome (ARDS) is a severe condition in which protective ventilation is a critical point in its management. Positive end expiratory pressure (PEEP) setting can be challenging for clinicians and high PEEP has been associated with better outcome in moderate and severe ARDS. Recently, recruitment to inflation ratio and airway closure have been investigated in order to help PEEP adjustment. However, ventilatory maneuvers are performed with a low level of PEEP and therefore expose to derecruitment and oxygen desaturation. So far, the risk of oxygen desaturation has not been investigated and risk factors are unknown. The aim of this study is to evaluate the prevalence of oxygen desaturation during ventilatory maneuvers at low level of PEEP in patients with moderate or severe ARDS
Status | Recruiting |
Enrollment | 50 |
Est. completion date | May 2024 |
Est. primary completion date | May 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - age : > 18 yo - inclusion criteria: ARDS, Mechanical ventilation, low PEEP maneuvers Exclusion Criteria: - refusal to participate |
Country | Name | City | State |
---|---|---|---|
France | CHU Amiens | Amiens |
Lead Sponsor | Collaborator |
---|---|
Centre Hospitalier Universitaire, Amiens | Centre Hospitalier VALENCIENNES |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | prevalence of oxygen desaturation | 24 months |
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