Temporomandibular Joint Disorders Clinical Trial
Official title:
Clinical and Magnetic Resonance Imaging Evaluation of Micro Fragmented Adipose Tissue Injection Combined With Bone Marrow Stem Cells on Healing of Temporomandibular Joint Internal Disc Derangement Without Reduction (Randomized Control Pilot Clinical Trial)
Verified date | April 2023 |
Source | Cairo University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Arthrocentesis of TMJ then injection of micro fragmented adipose tissue mixed with bone marrow aspirate on healing of TMJ internal disc derangement without reduction.
Status | Not yet recruiting |
Enrollment | 24 |
Est. completion date | July 1, 2025 |
Est. primary completion date | December 1, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - Patients with TMDs not previously surgically treated. - Patients with TMJ osteoarthritis assessed by clinical examination and magnetic resonance imaging. Exclusion Criteria: - Patients refuse to be enrolled in this study. - Patients with uncontrolled systemic disease. |
Country | Name | City | State |
---|---|---|---|
Egypt | Cairo university | Cairo | |
Egypt | Mohamed Talaat Abbas Hassan | Cairo |
Lead Sponsor | Collaborator |
---|---|
Mohamed Talaat Abbas Hassan |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Mandibular mouth opening | Measuring Maximum interincisal opening measured by plastic scale ruler in millimeter | 6 Months | |
Secondary | Post-operative pain | measuring pain by using visual analogue scale from (0 to 10) score where zero indicate no pain and 10 indicate worst pain | six months follow-up | |
Secondary | Joint sound | Clicking by clinical examination indicate ( present or absent ) of clicking | six months follow-up | |
Secondary | Lateral and protrusive movements | Measuring lateral and protrusive movements by using range of motion scale in millimeter | six months follow-up |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT03675659 -
Intra-articular Magnesium Sulfate for Tmj Dysfunction
|
Early Phase 1 | |
Completed |
NCT05740826 -
Correlation Between Cervical Spine Muscle Disorders and the Occurrence of Symptoms of Temporomandibular Joint Dysfunction
|
||
Recruiting |
NCT05006963 -
Tele-Rehabilitation in Patients With Temporomandibular Dysfunction
|
N/A | |
Active, not recruiting |
NCT06103851 -
Effect of Mask Use on Jaw Functionality
|
||
Not yet recruiting |
NCT02908568 -
Stimulation of the Proprioceptive Trigeminocardiac Reflex
|
Phase 2/Phase 3 | |
Completed |
NCT03119324 -
Low Level Laser Therapy in the Treatment of Temporomandibular Joint Disorders (TMJDs) Related Pain
|
N/A | |
Completed |
NCT02247063 -
Motor Cortex as a Research & Therapeutic Target in TMD
|
N/A | |
Recruiting |
NCT06046521 -
Impact of Temporomandibular Joint Dysfunction on Objective and Subjective Vocal Measures
|
||
Completed |
NCT00010621 -
Complementary Medicine Approaches to TMD Pain Management
|
Phase 2 | |
Completed |
NCT00009594 -
Alternative Medicine Approaches for Women With Temporomandibular Disorders
|
Phase 2 | |
Completed |
NCT06055855 -
Comparing Two-Needle vs. Surgery-Guided Arthrocentesis for TMJ Disorders
|
N/A | |
Not yet recruiting |
NCT06259344 -
Pain Science Education Administered in Full or Fractioned Dosage Modes for Temporomandibular Disorders
|
N/A | |
Recruiting |
NCT06035341 -
The Association Between Temporomandibular Disorders and Sacroiliac Joint Dysfunction
|
N/A | |
Completed |
NCT06005922 -
The Effectiveness of Temporomandibular Joint Mobilization and Exercise in Individuals With Chronic Neck Pain
|
N/A | |
Completed |
NCT05821985 -
Evaluation of the Effect of Dextrose Prolotherapy Versus Dry Needling Therapy
|
N/A | |
Completed |
NCT06034756 -
Temporomandibular Joint Problems and Core Stabilization
|
||
Completed |
NCT03576079 -
Effect of Laser Therapy Versus Anterior Re-positioning Splint in the Treatment of Disc Displacement With Reduction
|
N/A | |
Completed |
NCT04557878 -
Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patients With Disc Displacement Without Reduction
|
Phase 2 | |
Completed |
NCT04477122 -
Effects of Radial Shock Wave Therapy in the Treatment of Temporomandibular Joint Syndrome.
|
N/A | |
Completed |
NCT00237042 -
Managing Temporomandibular Disorder (TMD) Symptoms
|
N/A |