Mechanical Ventilation Complication Clinical Trial
Official title:
Effects of Tracheal Suctioning With or Without Expiratory Pause Maneuver in Children Submitted to Invasive Mechanical Ventilation: a Randomized Crossover Clinical Trial
NCT number | NCT05805475 |
Other study ID # | 2022-0072 |
Secondary ID | |
Status | Recruiting |
Phase | N/A |
First received | |
Last updated | |
Start date | April 1, 2023 |
Est. completion date | March 31, 2024 |
The purpose of this study is to evaluate the efficacy of tracheal suctioning associate with expiratory pause maneuver in children on invasive mechanical ventilation.
Status | Recruiting |
Enrollment | 10 |
Est. completion date | March 31, 2024 |
Est. primary completion date | October 1, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 1 Month to 2 Years |
Eligibility | Inclusion Criteria: - Children at invasive mechanical ventilation for more than 24 hours; - Under the effect of neuromuscular blocker (level of sedation assessed using the Comfort B Scale with a score <10 and without a cough reflex); - Endotracheal suctioning in a period > 2h before the application of the technique. Exclusion Criteria: - Patients with undrained pneumothorax or hemothorax, or presence of subcutaneous emphysema; - Hemodynamic instability (hypotension refractory to treatment) - Need of frequent endotracheal suctioning |
Country | Name | City | State |
---|---|---|---|
Brazil | Hospital de Clínicas de Porto Alegre | Porto Alegre | Rio Grande Do Sul |
Lead Sponsor | Collaborator |
---|---|
Hospital de Clinicas de Porto Alegre |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Heart rate | Heart rate in beats per minute (bpm) | Baseline, immediately after suctioning and after 30 minutes | |
Other | Arterial blood pressure | Systolic and diastolic blood pressure in millimeters of mercury (mmHg) | Baseline, immediately after suctioning and after 30 minutes | |
Other | Oxygen saturation | Oxygen saturation in percentage (%) | Baseline, immediately after suctioning and after 30 minutes | |
Primary | Weight of endotracheal suctioning | Weight of endotracheal suctioning in milligrams | Immediately after suctioning | |
Secondary | Peak inspiratory pressure | Peak inspiratory pressure in centimeters of water (cmH2O) | Baseline and 30 minutes | |
Secondary | Plateau pressure | Plateau pressure in centimeters of water (cmH2O) | Baseline and 30 minutes | |
Secondary | Tidal volume | Tidal volume in milliliters (ml) | Baseline and 30 minutes | |
Secondary | Dynamic compliance | Dynamic compliance in milliliters per kilograms per centimeters of water (mL/kg/cmH2O) | Baseline and 30 minutes | |
Secondary | Airway resistance | Inspiratory and expiratory resistance in centimeters of water per liter (cmH2O/L) | Baseline and 30 minutes | |
Secondary | Auto-positive end-expiratory pressure (auto-PEEP) | Auto-PEEP in centimeters of water (cmH2O) | Baseline and 30 minutes |
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