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NCT05695222 Clinical Trial

Cutaneous Squamous Cell Carcinoma Staging Study

Cutaneous Squamous Cell Carcinoma Clinical Trial

Official title:
Comparison of the Prognostic Capacity of Existing Staging Systems for Cutaneous Squamous Cell Carcinoma

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT05695222
Other study ID # 291683
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date May 1, 2023
Est. completion date November 2024

Study information
Verified date February 2024
Source Queen Mary University of London
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Cutaneous squamous cell carcinoma (CSCC) is the second most common form of skin cancer, and one of the most common cancers worldwide. The majority of CSCCs are easily removed by surgery and have excellent prognosis. However, a small subset has poor outcomes, including secondary spread in the body (metastasis) and death. The investigators will look at existing CSCC in people from two UK dermatology centres. The investigators will then evaluate the accuracy of current staging systems in predicting risk of poor outcomes in people. The investigators hope that this project will improve the management of patients with CSCC by validating the predictive power of currently available histological staging classifications for cSCC. In the second stage of the study, The investigators will see whether better prediction tools can be found.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 1500
Est. completion date November 2024
Est. primary completion date November 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 120 Years
Eligibility Inclusion Criteria: - Over 18 years old with diagnosis of CSCC Exclusion Criteria: - Patients who decline for their data to be used for research purposes

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• This is not an interventional study
This is not an interventional study

Locations
Country Name City State
United Kingdom Dr Emilia Peleva London

Sponsors (1)
Lead Sponsor Collaborator
Queen Mary University of London

Country where clinical trial is conducted

United Kingdom, 

Outcome
Type Measure Description Time frame Safety issue
Primary Recurrence or metastasis Proportion of patients developing cutaneous squamous cell carcinoma locoregional recurrence, nodal or distant metastases 4 years
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