Clinical Trials Logo

Clinical Trial Summary

Assessment of postoperative pain and treatment success after vital pulp therapy versus root canal treatment in mandibular molar with signs and symptoms of irreversible pulpitis. the null hypothesis, there is no difference will be observed in the pain level and treatment success between two treatments.


Clinical Trial Description

After proper clinical and radiographic examination. Teeth will be anesthetized and isolated using a rubber dam. The operative field will be disinfected. Total caries removal will be done from outside making margin caries free to inside. the new diamond bur will be used to remove the last layer and exposed the pulp tissue. Exposed pulp will be inspected under a dental operating microscope and hemostasis will be obtained. The teeth will be randomized into 2 intervention groups (VPT or RCT). Treatment will be finalized, and teeth will be restored with resin-modified glass ionomer followed by composite resin at the same appointment. Ibuprofen 400mg will be prescribed to the patient if needed. Patients will be asked to record postoperative pain after treatment on the pain score sheet. ;


Study Design


Related Conditions & MeSH terms

  • Pulpitis
  • Symptomatic Irreversible Pulpitis

NCT number NCT05681494
Study type Interventional
Source Cairo University
Contact Amany IA mohamed, phd
Phone 01099300346
Email amany.ahmed@dentistry.cu.edu.eg
Status Not yet recruiting
Phase N/A
Start date February 26, 2023
Completion date June 26, 2024

See also
  Status Clinical Trial Phase
Completed NCT04552132 - Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator N/A
Recruiting NCT05338671 - Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment Phase 4
Completed NCT04186897 - Occlusal Reduction Effect on Postendodontic Pain N/A
Recruiting NCT03725579 - Anesthetic Efficacy of 2% Mepivacaine Versus 4% Articaine Phase 2/Phase 3
Completed NCT03692039 - Comparison Between M-Pro and ProTaper Next N/A
Not yet recruiting NCT03716635 - Effect of Cryotherapy on Postoperative Pain N/A
Completed NCT05199181 - Full Pulpotomy in Mature Teeth With Symptomatic Irreversible Pulpitis as a Routine Treatment in the Primary Care Clinics N/A
Completed NCT03553641 - The Effect of Central Sensitization on Assessment Capacity of Patients
Not yet recruiting NCT03890835 - Pulpotomy in Mature Permanent Molars Using Biodentine Versus MTA N/A
Completed NCT03335007 - Pretreatment Aceclofenac Effect on Pain and Analgesic Intake After Endodontic Treatment Phase 2/Phase 3
Not yet recruiting NCT05238727 - Volume Increase Versus Supplemental 4% Articaine Buccal Infiltration on Mepivacaine Inferior Alveolar Nerve Block Success N/A
Not yet recruiting NCT04608981 - Effect of Diclofenac Potassium Versus Prednisolone on Post-endodontic Pain and Pulpal IL-8 Expression Phase 4
Not yet recruiting NCT06298383 - The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain N/A
Completed NCT05982392 - Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain Phase 2/Phase 3
Completed NCT05306470 - Ethyl Chloride Versus 5% Lidocaine for Topical Anesthesia of Oral Mucosa N/A
Completed NCT05488925 - Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block. Phase 4
Completed NCT04961268 - Effect of Preoperative Oral Tramadol on Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis N/A
Completed NCT04119661 - Postendodontic Pain on Using Max-i-Probe vs NaviTip as Irrigation Needles N/A
Completed NCT04202406 - Preoperative Acetaminophen- Caffeine- Codeine Combination and Anaesthetic Success in Patients With Acute Pulpitis N/A
Not yet recruiting NCT04593160 - Efficacy of Preoperative Diclofenac Potassium- Acetaminophen Combination on Anesthetic Success in Patients With Symptomatic Irreversible Pulpitis: a Randomized Controlled Trial N/A