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NCT05537974 Clinical Trial

Open Suction vs. Closed Suction in ARDS

Acute Respiratory Distress Syndrome Clinical Trial

Official title:
Effect of Endotracheal Aspiration on End-expiratory Lung Volume in Patients With ARDS, Comparison of Open vs. Closed Suction, A Randomize Cross-over Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05537974
Other study ID # IGHCEAH-ICU-7
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date September 15, 2022
Est. completion date October 31, 2022

Study information
Verified date January 2023
Source Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The alveoli tend to collapse in patients with ARDS. Endotracheal aspiration may increase alveolar collapse by decreasing the end-expiratory lung volume. The hypothesis is that closed endotracheal aspiration led to less end-expiratory volume loss when compared to open endotracheal aspiration.

Recruitment information / eligibility
Status Completed
Enrollment 20
Est. completion date October 31, 2022
Est. primary completion date October 31, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: Mechanically ventilated due to ARDS Exclusion Criteria: Hemodynamically unstable Air leaks syndrome (pneumothorax) Higher level of FiO2 (>60%) Chronic obstructive pulmonary disease

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Endotracheal aspiration
Clearance of endotracheal secretions via a catheter.

Locations
Country Name City State
Turkey University of Health Sciences Turkey, Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital, Intensive Care Unit Izmir

Sponsors (1)
Lead Sponsor Collaborator
Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome
Type Measure Description Time frame Safety issue
Primary End expiratory lung volume (EELV) End expiratory lung impedance (EELI) will be measured wit electric impedance tomography. Change in EELI representative of change in EELV. One minute before suctioning, 1, 10, 20, 30 minutes after suctioning
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