Improved Bowel Cleansing Method for Colonoscopy Based on High Risk Population of Bowel Preparation

Bowel Preparation Before Colonoscopy Clinical Trial

Official title: Improved Bowel Cleansing Method for Colonoscopy Based on High Risk Population of Bowel Preparation#a Single-center,Endoscopist-blinded Randomized Controlled Trial

Status Recruiting

Clinical Trial Summary

The purpose of this study is to observe the difference in bowel preparation quality between compound sodium picosulfate#CSP combined with lactulose and polyethylene glycol electrolyte#PEG combined with lactulose in high-risk population.

Clinical Trial Description

The quality of bowel preparation is crucial for colonoscopy. Some high-risk factors for inadequate bowel preparation have been identified , including age >70, previous colon surgery, constipation, diabetes, Parkinson's disease, history of stroke or spinal cord injury, prior history of inadequate bowel preparation, body mass index (BMI) >25, use of tricyclic antidepressant or narcotics. Patients were considered as high risk if they have any of the above factors.This is a single-center ,endoscopist-blinded study to compare the efficacy of CSP combined with lactulose and PEG combined with lactulose in bowel preparation. In colonoscopy procedures, endoscopists who were blinded to the intervention evaluated the overall quality of colonoscopy cleaning according to the Boston Bowel Preparation Scale. Patients' tolerance, defecation, adverse events and adenoma detection rate (ADR) were also evaluated. ;

Related Conditions & MeSH terms

• Bowel Preparation Before Colonoscopy

• NCT number: NCT05498714
• Study type: Interventional
• Source: Renmin Hospital of Wuhan University
• Contact: Mingkai Chen, Ph.D & M.D
• Phone: 13720330580
• Email: chenmingkai@whu.edu.cn
• Status: Recruiting
• Phase: N/A
• Start date: July 18, 2022
• Completion date: June 30, 2023