Clinical Trials Logo
  1. Home
  2. Other
  3. NCT05220995
  4. Details
NCT05220995 Clinical Trial

The Effects of Miminal Stimulation Protocol on Preimplantation Genetic Screening

Preimplantation Genetic Screening Clinical Trial

Official title:
The Effects of Miminal Stimulation Protocol on Clinical Outcomes of Advanced Maternal Aged Women With Preimplantation Genetic Screening

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05220995
Other study ID # 31.01.2022
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date May 15, 2021
Est. completion date January 25, 2022

Study information
Verified date January 2022
Source Nigde Omer Halisdemir University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

PGS has been the most effective method for embryo selection in IVF cycles. Euploidy rates decrease significantly with advancing maternal age (AMA). The dosage of gonadotropins also may be increased to recruit an adequate number of follicles in AMA women, minimal Stimulation Protocol (MSP) with the new combination of human menopausal gonadotrophin (hMG) and clomiphene citrate (CC) for controlled ovarian hyperstimulation is defined for poor ovarian response women. The aim of this study is to show minimal stimulation protocol affect euploidy and pregnancy rates in preimplatation genetic screening (PGS) cycles with single embryo transfer.

Recruitment information / eligibility
Status Recruiting
Enrollment 200
Est. completion date January 25, 2022
Est. primary completion date January 23, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 38 Years to 45 Years
Eligibility Inclusion Criteria: Advanced maternal aged - Exclusion Criteria: Severe male factor, endometriosis, and absolute tubal factor were excluded in this study. -

Study Design

Related Conditions & MeSH terms

  • Preimplantation Genetic Screening

Intervention

Genetic:
• protocol
ovarian stimulation protocols on euploid rates were compared.

Locations
Country Name City State
Turkey Gokalp Oner Kayseri Gevher Nesibe
Turkey Gokalp Oner Kayseri Gevher Nesibe

Sponsors (1)
Lead Sponsor Collaborator
Gokalp Oner

Country where clinical trial is conducted

Turkey, 

Outcome
Type Measure Description Time frame Safety issue
Primary euploid rates the effects of different stimulation protocols on euploid rates 3 months
Secondary pregnancy rates the effects of different stimulation protocols on pregnancy rates 3 months
See also
  Status Clinical Trial Phase
Active, not recruiting NCT04621773 - Live Birth Rate in Patients With Unexplained Recurrent Pregnancy Loss
Recruiting NCT03976544 - Natural Cycle Versus Hormone Replacement Therapy Cycle for a Frozen-thawed Embryo Transfer in PGT Patients Phase 4
Terminated NCT03173885 - Investigating the Cryopreserved Blastocyst's ImplantatiOn Potential After Genetic Screening N/A
Completed NCT03001648 - Cumulative Live Birth Rates in Patients With Repeated Implantation Failure (RIF) Undergoing Preimplantation Genetic Screening (PGS ) N/A
Completed NCT03062969 - The Transition From Blastomere to Trophectoderm Biopsy: Comparing Two PGS Strategies N/A