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Application of ctDNA in the Evaluation of Curative Effect and Prognosis of SCLC Patients

Small Cell Lung Cancer Extensive Stage Clinical Trial

Official title:
Application of Circulating Tumor (ctDNA) in the Evaluation of Curative Effect and Prognosis of Small Cell Lung Cancer (SCLC) Patients

Clinical Trial Summary

The purpose of this study is to evaluate the application value of circulating tumor DNA(ctDNA) with efficacy evaluation and prognostic assessment in patients with unresectable SCLC, who were receiving radiotherapy and chemotherapy treatment.

Clinical Trial Description

1. According to each point in time of ctDNA, to analyze the dynamic changes of tumor burden and clonal subtypes which to evaluate the application value of ctDNA in curative efficacy evaluation. 2. Compare the two time points before and after radiotherapy and chemotherapy treatment of the cell free DNA (cfDNA) concentration and tumor burden, analysis the correlation between the changes and prognosis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05066945
Study type Observational
Source Xiangya Hospital of Central South University
Contact Deng
Phone 13574888840
Email yogurt1015@csu.edu.cn
Status Not yet recruiting
Phase
Start date January 1, 2022
Completion date December 31, 2026
View Details
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