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A Phase 2 Trial of Neoadjuvant Modified FOLFIRINOX Chemotherapy for Resectable Pancreatic Adenocarcinoma

Resectable Pancreatic Adenocarcinoma Clinical Trial

Official title:
A Phase 2 Trial of Neoadjuvant Modified FOLFIRINOX Chemotherapy for Resectable Pancreatic Adenocarcinoma

Clinical Trial Summary

Within the next decade, pancreatic ductal adenocarcinoma (PDAC) is expected to rise to the second leading cause of cancer-related mortality. To increase the survival, various peri-operative treatments have been tested, and adjuvant FOLFIRINOX or gemcitabine plus capecitabine is now standard of care after surgical resection for localized PDAC. Even with superior survival among various disease extent of PDAC, resectable PDAC still shows poor outcomes with surgery followed by adjuvant chemotherapy. This phase II study is investigating the role of modified-FOLFIRINOX as neoadjuvant treatment for resectable PDAC.

Clinical Trial Description

This phase II study is designed to evaluate the efficacy and safety of modified FOLFIRINOX as neoadjuvant treatment for resectable pancreatic cancer. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05066802
Study type Interventional
Source Yonsei University
Contact Choong-kun Lee
Phone +82-2-2228-8133
Email cklee512@yuhs.ac
Status Recruiting
Phase Phase 2
Start date May 11, 2020
Completion date May 31, 2023
View Details
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