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Investigate the Relationship Between Inflammatory and Coagulation in SAH CSF

Subarachnoid Hemorrhage, Aneurysmal Clinical Trial

Official title:
Inhibition of Caspase-1 Reduces Pyroptotic Neuroinflammation and Tissue Factor-Induced Cerebrospinal Fluid Circulation Impairment After Subarachnoid Hemorrhage

Clinical Trial Summary

Investigate the role of inflammasome and blood coagulation response in human cerebrospinal fluid after subarachnoid hemorrhage.

Clinical Trial Description

Investigate the role of inflammasome and blood coagulation response in human cerebrospinal fluid after subarachnoid hemorrhage (SAH). 1.40 patients with SAH will be included. The CSF will used for ELISA test for inflammatory factors and cogulation factors. 2.CSF obtained from 4 patients with non-neuroloogical disease with 4 addittional SAH patients will be used for Mass Spectrometry ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04938414
Study type Observational
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact
Status Completed
Phase
Start date December 1, 2020
Completion date October 1, 2021
View Details
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