Transversus Abdominis Plane Block Versus Quoadratus Lumborum Block on Infants

Transversus Abdominis Plane Block Clinical Trial

Official title:

Comparison of Postoperative Analgesic Efficiency of Transversus Abdominis Plane Block and Quoadratus Lumborum Block on Infants Who Underwent Single Sided Inguinal Hernia Repair: A Randomised Controlled Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04927624
• Other study ID #: 33334
• Status: Recruiting
• Phase: N/A
• Start date: June 1, 2021
• Est. completion date: October 15, 2021

Study information

• Verified date: June 2021
• Source: Sisli Hamidiye Etfal Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

we aimed to compare the effects of TAPB and QLB on postoperative pain score and analgesic consumption in infants who underwent unilateral inguinal hernia surgery.

Description:

Infants are more sensitive to the side effects of general anesthesia than older children. This may be associated with the incomplete maturation of organ systems effective in pharmacodynamics. Regional anesthesia applications provide safe and effective analgesia by reducing the need for opioids. Regional anesthesia applications in infants require experience and complication rates due to central blocks are high. However, in recent years, the use of ultrasound (USG) has increased the use of safe and effective trunk blocks. There are studies on the use of Transversus Abdominis Plan Block (TAPB) and Quadratus Lumborum Block (QLB) in children. However, there is no comparative study on its use in infants.

In our study, we aimed to compare the effects of TAPB and QLB on postoperative pain score and analgesic consumption in infants who underwent unilateral inguinal hernia surgery.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: October 15, 2021
• Est. primary completion date: September 30, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 1 Month to 12 Months

Eligibility

Inclusion Criteria:

• 1 month to 1 year

• who were scheduled for unilateral inguinal hernia operation

• American Society of Anesthesiologists (ASA) physical score I-II

Exclusion Criteria:

• Patients with ASA II-IV

• coagulopathy

• skin infection at the block application site

• bupivacaine allergy

• bilateral inguinal hernia operation

• additional operation in different region

• laparoscopic inguinal hernia operation

• younger than 1 month

• with a history of prematurity

Related Conditions & MeSH terms

• Transversus Abdominis Plane Block

Intervention

Procedure:
• transversus abdominis plane block
The transversus abdominis plane (TAP) block was first introduced by Rafi et al. in 2001 as a landmark-guided technique via the triangle of Petit to achieve a field block. It involves the injection of a local anesthetic solution into a plane between the internal oblique muscle and transversus abdominis muscle. Since the thoracolumbar nerves originating from the T6 to L1 spinal roots run into this plane and supply sensory nerves to the anterolateral abdominal wall , the local anesthetic spread in this plane can block the neural afferents and provide analgesia to the anterolateral abdominal wall.
• quoadratus lumborum block
quoadratus lumborum block

Locations

Country	Name	City	State
Turkey	Sisli Etfal Research and Training Hospital	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Sisli Hamidiye Etfal Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	FLACC	Face, Legs, Activitiy, Cry, Consolability score	up to 24 hours
Primary	first analgesic need times	time of first analgesic need after surgery	up to 24 hours
Secondary	frequency of need for analgesics	Frequency of analgesic requirement in the first 24 hours after the operation	up to 24 hours
Secondary	complications	post-operative anesthetic complications	up to 24 hours