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Olfactory Outcomes of Dupilumab Treatment for Nasal Polyposis

Chronic Rhinosinusitis With Nasal Polyps Clinical Trial

Official title:
The 'Real World' Olfactory Outcomes Treating Nasal Polyposis With Dupilumab

Clinical Trial Summary

The study aims to investigate the olfactory TDI score (Threshold, Discrimination, Identification) using the Sniffin' sticks test for patients with chronic rhinosinusitis with nasal polyps (CRSwNP) on dupilumab. Twenty-seven adult patients will be followed up during the treatment with dupilumab on three visits to the Otolaryngology Clinic (Baseline, 3 months and 6 months). The primary endpoint will be the TDI score. Nasal polyp score, Quality of Olfactory Disorders - negative symptoms (QOD-NS symptom scores), SNOT-22 will be secondary endpoints.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04869436
Study type Interventional
Source Lawson Health Research Institute
Contact Taciano Rocha, PhD
Phone +15196466100
Email taciano.rocha@sjhc.london.on.ca
Status Recruiting
Phase Phase 4
Start date July 19, 2021
Completion date December 1, 2024
View Details
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