Renal Tubular Disorders in Egyptian Children

Renal Tubular Disorders in Children Clinical Trial

Official title:

Patterns of Renal Tubular Disorders in Egyptian Children: a Single Center Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04845815
• Other study ID #: Soh-Med-21-04-04
• Status: Completed
• Start date: April 23, 2021
• Est. completion date: January 7, 2022

Study information

• Verified date: April 2021
• Source: Sohag University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Renal tubules play an important role in fluid, electrolyte, and acid-base homeostasis. Defect of these functions can give rise to a host of disorders. These disorders can lead to life threatening disturbances in electrolytes and acid-base balance. In Egypt, there is little data about these disorders. Many of these cases are diagnosed late, therefore Early suspicion for diagnosis can improve the overall clinical outcome of these children.

Description:

Renal tubules play an important role in fluid, electrolyte, and acid-base homeostasis. Defect of these functions can give rise to a host of disorders. These disorders can lead to life threatening disturbances in electrolytes and acid-base balance. In Egypt, there is little data about these disorders. Many of these cases are diagnosed late, therefore Early suspicion for diagnosis can improve the overall clinical outcome of these children. As a result, starting management early will help those children have a better life. Therefore awareness about these disorders and long-term outcome is really important. The investigators present the clinical characterizations of many tubular disorder and the follow up in our center. The aim of this study is to reveal the different clinical presentations and the main lab features of renal tubular disorders in children to promote early recognition and management.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 58
• Est. completion date: January 7, 2022
• Est. primary completion date: December 9, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 1 Month to 18 Years

Eligibility

Inclusion Criteria:

• All children aged from one month to 18 years who have renal tubular disorders.

Exclusion Criteria:

• Children who have renal tubular disorders secondary to drugs, intoxication, obstructive uropathy or transient in nature.

Related Conditions & MeSH terms

• Disease
• Renal Tubular Disorders in Children

Locations

Country	Name	City	State
Egypt	pediatric department, Sohag university hospital	Sohag

Sponsors (1)

Lead Sponsor	Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	weight	in kilograms	1 years
Primary	Glomerular function	The glomerular function was assessed by estimated glomerular filtration rate (eGFR) calculated using Schwartz formula. Chronic kidney disease (CKD) was defined in the presence of a permanent reduction in GFR (e-GFR; <60 ml/min/1.73 m2 Kidney Disease Outcomes Quality Initiative < stage 3).	1 years
Primary	height	in meters	1 years