| Eligibility |
Inclusion Criteria:
- 1. After fully understanding the purpose and significance of the trial, the patients
voluntarily participated in the trial and signed the informed consent;
2. The type of operation was general anesthesia and thoracoscopic lobectomy;
3. Age 18-75 years old, including boundary value, gender is not limited;
4. BMI 18-26kg / m2;
5. ASA grade I-II; no mental disorder, normal consciousness, normal communication;
6. No contraindications of methylprednisolone and dihydroxypropyltheophylline.
Exclusion Criteria:
- 1. There were diseases of immune, endocrine, nervous and mental system before
operation, and serious dysfunction of heart, liver and kidney;
2. Take immunosuppressive drugs and non steroidal anti-inflammatory drugs before
operation;
3. Respiratory tract infection (cough, expectoration, suffocation, etc.) in recent 1
month; pneumonia, bronchitis, etc. on CT;
4. History of chronic pulmonary disease, including but not limited to asthma,
pulmonary abscess, tuberculosis, chronic bronchitis, etc;
5. FEV1 < 50%;
6. Oxygen saturation was lower than 90% and airway pressure was higher than 40 cm H20;
7. Continuous hypotension or hypertension during the operation; intraoperative blood
loss > 1000ml;
8. Allergic to methylprednisolone or dihydroxypropyltheophylline;
9. There are any other situations that the researchers think are not suitable for
inclusion.
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