Omega-3 Supplementation Combined With Endurance Training Improve Running Economy in Recreational Runners.

Effect of Omega-3 Supplementation on Exercise Performance and Muscle Tissue Functions Clinical Trial

Official title:

12 Weeks of Omega-3 Supplementation Combined With Endurance Training Improve Running Economy in Recreational Runners. The Potential Role of the Myokines-NO Pathway.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04780451
• Other study ID #: 2018/31/N/NZ7/02962
• Status: Completed
• Phase: Phase 3
• Start date: September 16, 2020
• Est. completion date: March 2, 2021

Study information

• Verified date: February 2021
• Source: Gdansk University of Physical Education and Sport
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Recreational male runners participated in 12 weeks training and omega-3 supplementation programme. Before starting and at the end of the 12-week cycle, the runners performed an increasing intensity treadmill test where oxygen uptake and VO2 peak were assessed.

Description:

40 healthy, recreational male runners participated in 12 weeks training and supplementation programme. The training protocol was built based on undulatory load manipulation 3:1, which was suggested to be effective to prevent overtraining and stress due to oscillations between volume/intensity. Throughout the study all participants took 4 identical-looking capsules per day (2 in the morning and 2 in the evening) containing either omega-3 fatty acids or medium chain triglycerides as placebo in total amount of 4g of fat per day. Before starting and at the end of the 12-week cycle, the runners performed an increasing intensity treadmill test where oxygen uptake and VO2 peak were assessed. Additionally, blood was collected to determine the concentrations of selected proteins (including eNOS, irisin, adiponectin) that may be associated with potential changes in participants' oxygen uptake during the treadmill test.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: March 2, 2021
• Est. primary completion date: December 20, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 29 Years to 42 Years

Eligibility

Inclusion Criteria:

• non smoking

• no chronic diseases

• no supplements and medicines

• personal best in 10km run between 35 and 59 min at the turn of 2016 and 2020 y

Exclusion Criteria:

-

Related Conditions & MeSH terms

• Effect of Omega-3 Supplementation on Exercise Performance and Muscle Tissue Functions

Intervention

Dietary Supplement:
• Omega-3 supplementation in recreational runners
Male recreational runners participated in 12 weeks of endurance training combined with omega-3 fatty acids supplementation. Before starting and at the end of the 12-week cycle, the runners performed an increasing intensity treadmill test where oxygen uptake and VO2 peak were assessed.

Locations

Country	Name	City	State
Poland	Gdansk University of Physical Education and Sport	Gdansk

Sponsors (3)

Lead Sponsor	Collaborator
Gdansk University of Physical Education and Sport	Medical University of Gdansk, University of Southampton

Country where clinical trial is conducted

Poland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	changes in oxygen consumption during running test		between 10 and 25 minutes of the running test