Cyanoacrylate Tissue Adhesives Versus Silk Suture at the Palatal Donor Site of Sub Epithelial Connective Tissue Graft

The Effect of Local Aplication of Cayanoacrylate Tissue Adhesives on Improving the Healing Clinical Trial

Official title:

Evaluation of Post Operative Pain, Early Wound Healing, and the Time of Application of Cyanoacrylates Tissue Adhesives Versus Silk Sutures at the Palatal Donor Area of Subepithelial Connective Tissue Grafts (CTG) A Randomized Clinical Trial: Comparative Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04780360
• Other study ID #: 567
• Status: Recruiting
• Phase: N/A
• Start date: February 1, 2021
• Est. completion date: December 1, 2021

Study information

• Verified date: March 2021
• Source: Cairo University
• Contact: Mohamed S Mohamed Ibrahium Abdullah, Invistegator
• Phone: 01283626196
• Email: dr.mohamed15.ms[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Subepithelial connective tissue grafts (CTG) are considered the gold standard procedure with proven clinical success when it comes to gingival augmentation aims to to improve periodontal health, which can enhance the long-term prognosis of teeth by obtaining soft tissue coverage of exposed root surfaces and/or augmentation the dimensions of gingival tissue. The procedure require harvesting tissue from a the palate, which increases the complexity of the procedure and patient discomfort. Complications after harvesting a graft would be pain, inflammation, bleeding, flap necrosis and infection in the donor site.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 20
• Est. completion date: December 1, 2021
• Est. primary completion date: December 1, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• Patients with mucogingival defects scheduled for sub epithelial connective tissue graft

• Age at least 18 years.

• Not having any systemic disease that could compromise wound healing

• No periodontal surgery on the experimental sites.

• No smoking,

• No pregnancy or lactation

Exclusion Criteria:

• Patients with coagulation disorders

• patients on corticosteroids, with uncontrolled diabetes, or with any systemic disease that precluded periodontal surgery

• patients with a history of contact dermatitis to formaldehyde

• Loss of maxillary premolars and molars

• Medications or antibiotics used in the previous 6 months

• Pregnancy or lactation

• Smoking

Related Conditions & MeSH terms

• The Effect of Local Aplication of Cayanoacrylate Tissue Adhesives on Improving the Healing

Intervention

Procedure:
• Cayanoacrylate tissue adhesives
Cyanoacrylates are a family of strong fast-acting adhesives with industrial, medical, and household uses. They are various esters of cyanoacrylic acid. The acryl groups in the resin rapidly polymerize in the presence of water to form long, strong chains
• Silk suture
Non Absorbalble suture materiel used to fixed the edges of the incision in place until healing

Locations

Country	Name	City	State
Egypt	Faculty of Dentistry, Cairo Universty	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Early Wound Healing	Measured By Modified Early Wound Healing Index	1 week