Ultrasonography Guided Brain Lesions Resection:

Patients Who Are Diagnosed to Have Intracranial Lesions Clinical Trial

Official title:

Ultrasonography Guided Brain Lesions Resection: a Tool for a Real Time Intraoperative Neuronavigation

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04569526
• Other study ID #: intra operative ultrasound
• Status: Not yet recruiting
• Start date: September 25, 2020
• Est. completion date: December 30, 2021

Study information

• Verified date: September 2020
• Source: Assiut University
• Contact: sarah ahmed saad tawfik, Rdr
• Phone: 01099842575
• Email: sarahahmedsaad[@]gmail.com
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

1. Evaluate the clinical value of intraoperative ultrasonography as a real-time guidance

2. Combination of data of MRI Tractography and intra operative ultrasonography will be useful in good localization of lesions or not .

3. Maximal safe resection .

Description:

Accurate pre and intraoperative localization of Brain lesions is a challenge in neurosurgery specially deep intra cerebral lesions. Stereotaxy and neuronavigator played a major role in preoperative and intraoperative evaluation of exact location of intra cerebral lesions, the main drawbacks of using steriotaxy and neuronavigator that they are time consuming, complicated and expensive.(1) Nowadays we use MRI Tractography as preoperative imaging to localize lesions and there relation to neural tracts specially in eloquent brain areas, and also intraoperative ultrasonography Which act as a real-time, unexpansive and relatively simple tool for intraoperative visualization of the lesion's location, size, extent and its relationship with the surrounding tissue, also it can reveal the lesion's blood supply, it can measure the rate and direction of arterial blood flow.(2,3,4) Intraoperative ultrasonic imaging was first applied as a real-time navigation system in neurosurgery in 1980. (5) In this research we will combine the use of preoperative MRI tractography with intra operative ultrasonography in accurate localization of brain lesions and its relation with important tracts and if this combination will be beneficial and add to the safety of excision of lesions or not.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 1
• Est. completion date: December 30, 2021
• Est. primary completion date: July 25, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 1 Month to 70 Years

Eligibility

Inclusion Criteria:

• Patients who are diagnosed to have Intracranial lesions Patients with recurrent lesions

Exclusion Criteria:

• Patients who are unfit for surgery Patients who have multifocal lesions

Related Conditions & MeSH terms

• Patients Who Are Diagnosed to Have Intracranial Lesions

Intervention

Device:
• use of intraoperative ultrasound
Ultrasonography guided brain lesions resection intra operatively for good localization

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Extent of resection of the lesion	Extent of resection of the lesion evaluated by comparing pre operative and post operative MRI	48 hours
Secondary	post operative complication	post operative complication evaluated by full neurological examination	one month

External Links

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