Multiple Sclerosis, Primary Progressive Clinical Trial
Official title:
Effect of Aerobic Exercises on Immune System in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) .It is the most common neurological disorders affecting young adults.Multiple sclerosis is an autoimmune disease that results in progressive neural degeneration. Cytokines play an important role in the pathogenesis and treatment of MS.
This research aims to evaluate the effect of aerobic exercises on the immune system
anti-inflammatory (IL-10) and pro inflammatory (IL-17) cytokines and its consequences on the
functional status in the Multiple Sclerosis patients.
Aerobic exercises are a term to describe planned, structured and repetitive physical activity
undertaken over a prolonged period to maintain or improve physical fitness and functional
capacity .
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03455582 -
Cognition Evolution and MRI Markers in PPMS Patients on 2 Years
|
N/A | |
| Active, not recruiting |
NCT04544449 -
A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis
|
Phase 3 | |
| Completed |
NCT06436131 -
The Effects of In-phase Bilateral Exercise in People With Progressive Multiple Sclerosis
|
N/A | |
| Recruiting |
NCT04918225 -
Motor Asymmetry in Progressive Multiple Sclerosis Patients
|
||
| Completed |
NCT02913157 -
Hydroxychloroquine in Primary Progressive Multiple Sclerosis
|
Phase 2 | |
| Completed |
NCT01982942 -
Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis
|
Phase 2 | |
| Recruiting |
NCT05204459 -
MS-ResearchBiomarkerS
|
||
| Completed |
NCT05663853 -
An Observational Biomarker Study in Multiple Sclerosis (MS) Patients
|
||
| Completed |
NCT01194570 -
A Study of Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis
|
Phase 3 | |
| Completed |
NCT02305264 -
Imaging of Intracerebral Inflammation in MS
|
N/A | |
| Completed |
NCT03679468 -
Improving Cognition in People With Progressive Multiple Sclerosis Using Aerobic Exercise and Cognitive Rehabilitation
|
N/A | |
| Recruiting |
NCT05496881 -
Exercise Effects in Multiple Sclerosis
|
N/A | |
| Completed |
NCT02506751 -
Open-label Study of Liothyronine in MS
|
Phase 1 | |
| Temporarily not available |
NCT02606929 -
Use of Well Known Drugs for New Destination - MS Improvement (MSNT)
|
Phase 0 | |
| Completed |
NCT03424538 -
The Effect of Neurorehabilitation Therapy on Postural Control, Mobility and Quality of Life in Multiple Sclerosis Patients
|
N/A | |
| Recruiting |
NCT05122559 -
Neuroprotection With N-acetyl Cysteine for Patients With Progressive Multiple Sclerosis
|
Phase 2 | |
| Completed |
NCT02988401 -
Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis
|
Phase 1/Phase 2 | |
| Completed |
NCT02632591 -
Use on Human Beings of Mix of Known Drugs for New Destination - MS Treatment
|
Phase 1 | |
| Completed |
NCT01917019 -
A Safety and Efficacy Study of Oral Prolonged-Release Fampridine (BIIB041) in Japanese Participants With Multiple Sclerosis
|
Phase 3 | |
| Completed |
NCT01433497 -
Efficacy and Safety of Masitinib in the Treatment of Progressive Multiple Sclerosis
|
Phase 3 |